General Information of the Compound
Compound ID
CP0257260
Compound Name
1-ethyl-7-fluoro-4-oxo-N-[(1R,2S)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]quinoline-3-carboxamide
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Structure
Formula
C22H27FN2O2
Molecular Weight
370.468
Canonical SMILES
CCn1cc(C(=O)N[C@@H]2C(C)(C)C3CC[C@]2(C)C3)c(=O)c2ccc(F)cc12
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InChI
InChI=1S/C22H27FN2O2/c1-5-25-12-16(18(26)15-7-6-14(23)10-17(15)25)19(27)24-20-21(2,3)13-8-9-22(20,4)11-13/h6-7,10,12-13,20H,5,8-9,11H2,1-4H3,(H,24,27)/t13?,20-,22-/m1/s1
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InChIKey
FMWROTRZBIZHIS-HVQVANDDSA-N
Physicochemical Property
logP
4.1051
Rotatable Bonds
3
Heavy Atom Count
27
Polar Areas
51.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71460308
ChEMBL ID
CHEMBL2152800
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 959.7 nM
   TI
   LI
   LO
   TS
Protein ID: PT00834, Cannabinoid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 17.2 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 7.3 nM
   TI
   LI
   LO
   TS