General Information of the Compound
| Compound ID |
CP0231014
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| Compound Name |
US9266883, 201
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| Structure |
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| Formula |
C17H15N5O2
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| Molecular Weight |
321.34
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| Canonical SMILES |
O=Cc1ccc2CCCCN(C(=O)Nc3ccc(cn3)C#N)c2n1
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| InChI |
InChI=1S/C17H15N5O2/c18-9-12-4-7-15(19-10-12)21-17(24)22-8-2-1-3-13-5-6-14(11-23)20-16(13)22/h4-7,10-11H,1-3,8H2,(H,19,21,24)
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| InChIKey |
MBNIEIXGGYJKIK-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000148 | Huh-7 | Homo sapiens (Human) | 1 |
| 1 |
IC50 > 3000 nM
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TI
LI
LO
TS
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