General Information of the Compound
| Compound ID |
CP0205441
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| Compound Name |
Ang IV
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| Synonyms |
(3-8)-5-Isoleucine-angiotensin II
(Des(Asp1,Arg2)-Ile5)angiotensin II
(Ile5)-angiotensin II (3-8)
(Isoleucine5)-angiotensin II hexapeptide
1-De-asp-2-de-arg-5-ile-angiotensin II
12676-15-2
23025-68-5
5-Isoleucine-angiotensin II 3-8-hexapeptide
ANGIOTENSIN I/II (3-8)
Ang IV
Angiotensin II (3-8)
Angiotensin II (3-8), human
Angiotensin IV
CHEMBL261120
Huamn angiotensin (3-8)
Human angiotensin IV
Human angiotensin hexapeptide (3-8)
Ile3-angiotensin IV
MLS000069773
Nle-angiv
VAL-TYR-ILE-HIS-PRO-PHE
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| Structure |
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| Formula |
C40H54N8O8
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| Molecular Weight |
774.92
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| Canonical SMILES |
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O
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| InChI |
InChI=1S/C40H54N8O8/c1-5-24(4)34(47-35(50)29(44-37(52)33(41)23(2)3)18-26-13-15-28(49)16-14-26)38(53)45-30(20-27-21-42-22-43-27)39(54)48-17-9-12-32(48)36(51)46-31(40(55)56)19-25-10-7-6-8-11-25/h6-8,10-11,13-16,21-24,29-34,49H,5,9,12,17-20,41H2,1-4H3,(H,42,43)(H,44,52)(H,45,53)(H,46,51)(H,47,50)(H,55,56)/t24-,29-,30-,31-,32-,33-,34-/m0/s1
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| InChIKey |
QSBGWDDCOJYQGY-KOQODJNWSA-N
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| CAS |
202203-97-2
22956-44-1
23025-68-5
24723-55-5
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01820, Aminopeptidase N
Protein ID: PT05116, Leucyl-cystinyl aminopeptidase
Protein ID: PT01197, Type-1 angiotensin II receptor
Clinical Information about the Compound