General Information of the Compound
| Compound ID |
CP0192479
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| Compound Name |
(5-Chloro-benzo[1,2,5]thiadiazol-4-yl)-(4,5-dihydro-1H-imidazol-2-yl)-amine
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| Synonyms |
5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole
5-chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole
5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
Sirdalud
Sirdalud (TN)
Ternelin
Tizanidina
Tizanidina [INN-Spanish]
Tizanidine
Tizanidine (INN)
Tizanidine [INN:BAN]
Tizanidinum
Tizanidinum [INN-Latin]
Zanaflex (TN)
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| Structure |
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| Formula |
C9H8ClN5S
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| Molecular Weight |
253.718
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| Canonical SMILES |
Clc1ccc2nsnc2c1NC1=NCCN1
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| InChI |
InChI=1S/C9H8ClN5S/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9/h1-2H,3-4H2,(H2,11,12,13)
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| InChIKey |
XFYDIVBRZNQMJC-UHFFFAOYSA-N
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| CAS |
51322-75-9
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02060, Alpha-1A adrenergic receptor
Protein ID: PT00644, Alpha-1B adrenergic receptor
Protein ID: PT01650, Alpha-2A adrenergic receptor
Protein ID: PT01598, Alpha-2C adrenergic receptor
Clinical Information about the Compound