General Information of the Protein
Protein ID
PT00644
Protein Name
Alpha-1B adrenergic receptor
Gene Name
I79_008739
Sequence
MHLSISDWIESGESKTEAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAIADLLFSFTVLPFSATLEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVIIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLHKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGK
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Organism
Cricetulus griseus, Chinese hamster, Cricetulus barabensis griseus
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
G3HDX1
Subcellular Location
Cell membrane
Membrane
Nucleus membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000006 , HEK293
Compound ID Compound Name Compound Formula
CP0147996
CHEBI:8093
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C9H13NO2
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0041905
2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)
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C9H9Cl2N3
 1
1
EC50 = 83 nM
   TI
   LI
   LO
   TS
CP0192479
(5-Chloro-benzo[1,2,5]thiadiazol-4-yl)-(4,5-dihydro-1H-imidazol-2-yl)-amine
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C9H8ClN5S
 1
1
EC50 = 322 nM
   TI
   LI
   LO
   TS
CP0108416
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
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C13H16N2
 1
1
EC50 = 364 nM
   TI
   LI
   LO
   TS
CP0041550
BRIMONIDINE
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C11H10BrN5
 1
1
EC50 = 943 nM
   TI
   LI
   LO
   TS