General Information of the Compound
Compound ID
CP0142785
Compound Name
2-[4-[butyl-[3-(4-chlorophenyl)-2-methoxyphenyl]sulfamoyl]-2,3-dimethylphenoxy]propanoic acid
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Structure
Formula
C28H32ClNO6S
Molecular Weight
546.085
Canonical SMILES
CCCCN(c1cccc(-c2ccc(Cl)cc2)c1OC)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C
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InChI
InChI=1S/C28H32ClNO6S/c1-6-7-17-30(24-10-8-9-23(27(24)35-5)21-11-13-22(29)14-12-21)37(33,34)26-16-15-25(18(2)19(26)3)36-20(4)28(31)32/h8-16,20H,6-7,17H2,1-5H3,(H,31,32)
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InChIKey
AGOONXNQGYHFDR-UHFFFAOYSA-N
Physicochemical Property
logP
6.47974
Rotatable Bonds
11
Heavy Atom Count
37
Polar Areas
93.14
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 54585901
ChEMBL ID
CHEMBL1760412
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00909, Peroxisome proliferator-activated receptor delta
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 19.95 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25.12 nM