General Information of the Compound
Compound ID
CP0130693
Compound Name
(R)-6-cyclohexyl-N-hydroxy-3-(3-(morpholine-4-carbonyl)-1,2,4-oxadiazol-5-yl)hexanamide
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Structure
Formula
C19H30N4O5
Molecular Weight
394.472
Canonical SMILES
ONC(=O)C[C@@H](CCCC1CCCCC1)c1nc(no1)C(=O)N1CCOCC1
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InChI
InChI=1S/C19H30N4O5/c24-16(21-26)13-15(8-4-7-14-5-2-1-3-6-14)18-20-17(22-28-18)19(25)23-9-11-27-12-10-23/h14-15,26H,1-13H2,(H,21,24)/t15-/m1/s1
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InChIKey
HLMFJGVJQBEIED-OAHLLOKOSA-N
Physicochemical Property
logP
2.2717
Rotatable Bonds
8
Heavy Atom Count
28
Polar Areas
117.79
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10222243
SID: 15223210
ChEMBL ID
CHEMBL525215
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01896, Bone morphogenetic protein 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 25 nM
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