General Information of the Compound
| Compound ID |
CP0095234
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| Compound Name |
(E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopropyl]-penta-2,4-dienoic acid
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| Synonyms |
AGN-190205
AGN-191659
AGN-191701
AGN-192326
AGN-192327
AGN-192509
AGN-192599
AGN-192870
AGN-194277
AGN-195393
AGN-4202
ALRT-326
ALRT-4204
LGD-4204
LGD-4326
NRX-194202
NRX-4204
RXR agonists (cancer/ diabetes), Vitae Pharmaceuticals
RXR agonists, Allergan/Parke-Davis
RXR agonists, Allergan/Pfizer
RXR ligands, ALRT
RXR ligands, Allergan
Retinoid X receptor agonists, ALRT
Retinoid X receptor agonists, Allergan
Rexinoid receptor agonist (cancer), NuRx
VTP-4204
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| Structure |
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| Formula |
C24H32O2
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| Molecular Weight |
352.518
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| Canonical SMILES |
C\C(\C=C\C1CC1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
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| InChI |
InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-18-15-24(18,6)17-9-10-19-20(14-17)23(4,5)12-11-22(19,2)3/h7-10,13-14,18H,11-12,15H2,1-6H3,(H,25,26)/b8-7+,16-13+
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| InChIKey |
BOOOLEGQBVUTKC-YWRSBGDESA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound