General Information of the Compound
Compound ID
CP0089002
Compound Name
N-[2-(4-fluorophenyl)ethyl]-7,8-dimethoxy-2-oxo-1H-quinoline-3-carboxamide
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Structure
Formula
C20H19FN2O4
Molecular Weight
370.38
Canonical SMILES
COc1ccc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c2c1OC
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InChI
InChI=1S/C20H19FN2O4/c1-26-16-8-5-13-11-15(20(25)23-17(13)18(16)27-2)19(24)22-10-9-12-3-6-14(21)7-4-12/h3-8,11H,9-10H2,1-2H3,(H,22,24)(H,23,25)
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InChIKey
VLNYVUQPQVEPDW-UHFFFAOYSA-N
Physicochemical Property
logP
2.6569
Rotatable Bonds
6
Heavy Atom Count
27
Polar Areas
80.42
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 23555594
SID: 126722694
ChEMBL ID
CHEMBL1822929
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00834, Cannabinoid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5 nM