General Information of the Compound
| Compound ID |
CP0072206
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| Compound Name |
NORTRIPTYLINE
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| Synonyms |
(2)10,11-Dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-.delta.5.gamma.-propylamine
10,11-Dihydro-5-(3-methylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptene
10,11-Dihydro-N-methyl-5H-dibenzo(a,d)cycloheptene-delta(5,gamma)-propylamine
10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Delta(5,gamma)-propylamine
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methylpropylamine
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine
5-(3-(Methylamino)propylidene)dibenzo(a,e)cyclohepta(1,5)diene
5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(alpha-Methylaminopropylidene)dibenzo(a,d)cyclohepta(1,4)diene
AVENTYL HCL
Acetexa
Allegron
Allegron (TN)
Altilev
Ateben
Avantyl
Aventyl
Aventyl (TN)
Demethylamitriptylene
Demethylamitriptyline
Demethylamitryptyline
Desitriptilina
Desitriptyline
Desmethylamitriptylin
Desmethylamitriptyline
Lumbeck
N-Methyl-3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)propylamin
NCI169453
Noramitriptyline
Noritren
Norpress (TN)
Nortrilen
Nortrilen (TN)
Nortriptilina
Nortriptilina [DCIT]
Nortriptylene hydrochloride
Nortriptyline
Nortriptyline (INN)
Nortriptyline [INN:BAN]
Nortriptylinum
Nortriptylinum [INN-Latin]
Nortryptiline
Nortryptyline
Pamelor
Pamelor (TN)
Pamelor hydrochloride
Psychostyl
Sensaval
Sensival Ventyl
Sensoval (TN)
Sesaval
Vividyl
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| Structure |
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| Formula |
C19H21N
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| Molecular Weight |
263.384
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| Canonical SMILES |
CNCCC=C1c2ccccc2CCc2ccccc12
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| InChI |
InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19/h2-5,7-11,20H,6,12-14H2,1H3
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| InChIKey |
PHVGLTMQBUFIQQ-UHFFFAOYSA-N
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| CAS |
72-69-5
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Protein ID: PT01049, Cytochrome P450 2C19
Protein ID: PT00817, Cytochrome P450 2D6
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Protein ID: PT02031, Voltage-dependent N-type calcium channel subunit alpha-1B
Clinical Information about the Compound