General Information of the Compound
Compound ID
CP0071473
Compound Name
Amudane
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Synonyms
(+)-Griseofulvin
7-Chloro-4,6,2'-trimethoxy-6'-methylgris-2'-en-3,4'-dione
Amudane
Biogrisin-FP
Curling fact or
Curling factor
Delmofulvina
FULVICIN P/G 165
FULVICIN P/G 330;Fulvicin Bolus (Veterinary)
Fulcin
Fulcine
Fulvican grisactin
Fulvicin
Fulvicin P/G
Fulvicin U F
Fulvicin U/F
Fulvicin-P/G
Fulvicin-U-F
Fulvicin-U/F
Fulvicin-U/F (Veterinary)
FulvicinUF
Fulvidex (Veterinary)
Fulvina
Fulvinil
Fulvistatin
Fungivin
GRISEOFULVIN, MICROCRYSTALLINE
GRISEOFULVIN, ULTRAMICROCRYSTALLINE
Greosin;Gresfeed
Gricin
Grifulin
Grifulvin
Grifulvin V
Gris PEG
Gris-PEG
GrisPEG
Grisactin
Grisactin Ultra
Griscofulvin
Grise ostatin
Grisefuline
Griseo
Griseofulvin
Griseofulvin [USAN:INN:BAN:JAN]
Griseofulvin and Alpha-IFN
Griseofulvin forte
Griseofulvin-forte
Griseofulvina
Griseofulvina [INN-Spanish]
Griseofulvine
Griseofulvine [INN-French]
Griseofulvinum
Griseofulvinum [INN-Latin]
Griseomix
Griseostatin
Grisetin
Grisofulvin
Grisovin
Grisovin (TN)
Grisovin FP
Grizeofulvin
Grysio
Guservin
Interacts with polymerized microtubules and associated proteins
Lamoryl
Likuden
Likunden
Murfulvin
NP-002466
Neo-Fulcin
Poncyl
Spirofulvin
Sporostatin
Sporostatin xan
ULTRAGRIS-165
ULTRAGRIS-330
USAF SC-2
Xuanjing
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Structure
Formula
C17H17ClO6
Molecular Weight
352.77
Canonical SMILES
COC1=CC(=O)C[C@@H](C)[C@]11Oc2c(C1=O)c(OC)cc(OC)c2Cl
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InChI
InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
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InChIKey
DDUHZTYCFQRHIY-RBHXEPJQSA-N
CAS
126-07-8
Physicochemical Property
logP
2.8103
Rotatable Bonds
3
Heavy Atom Count
24
Polar Areas
71.06
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 441140
SID: 14778634
ChEMBL ID
CHEMBL562
DrugBank ID
DB00400
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
Potency ~ 29092.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT03795, Solute carrier family 22 member 1
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( Griseofulvin )
Drug Name Griseofulvin
Indication
Ringworm infection
Approved