General Information of the Compound
| Compound ID |
CP0060392
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| Compound Name |
(R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide
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| Synonyms |
RKI-983
ROCK inhibitors, Mitsubishi Tanabe Pharma/Senju/Novartis
Rho-associated protein kinase inhibitors, Mitsubishi Tanabe Pharma/Senju/Novartis
SNJ-1656
Y-39983
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| Structure |
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| Formula |
C16H16N4O
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| Molecular Weight |
280.331
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| Canonical SMILES |
C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
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| InChI |
InChI=1S/C16H16N4O/c1-10(17)11-2-4-12(5-3-11)16(21)20-14-7-9-19-15-13(14)6-8-18-15/h2-10H,17H2,1H3,(H2,18,19,20,21)/t10-/m1/s1
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| InChIKey |
JTVBXQAYBIJXRP-SNVBAGLBSA-N
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| CAS |
199433-58-4
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound