Brief Information of the Compound and Protein
Compound Name
(R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide
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PubChem ID
CID: 9810884
SID: 14848722
Canonical SMILES
C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
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Compound Formula C16H16N4O
Compound Structure
Protein Name
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000333 GTM-3 Homo sapiens (Human)  1
1
EC50 = 790 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 30 nM
2 IC50 = 120 nM
3 Ki = 28 nM