General Information of the Compound
Compound ID |
CP0052888
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Compound Name |
3-(imidazo[1,2-b]pyridazin-6-ylmethyl)-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine
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Structure |
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Formula |
C15H12N10
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Molecular Weight |
332.331
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Canonical SMILES |
Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4nccn4n3)c2n1
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InChI |
InChI=1S/C15H12N10/c1-23-8-10(6-18-23)12-7-17-14-15(19-12)25(22-20-14)9-11-2-3-13-16-4-5-24(13)21-11/h2-8H,9H2,1H3
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InChIKey |
UCCNXLVEXBEUPI-UHFFFAOYSA-N
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Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01201, Hepatocyte growth factor receptor
Cell Viability or Cytotoxicity Assay
Cell Line ID | Cell Line Name | Cell Line Organism | |
CL000450 | NCI-H441 | Homo sapiens (Human) | 1 |
1 |
IC50 = 443 nM
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