Brief Information of the Compound and Protein
Compound Name
3-(imidazo[1,2-b]pyridazin-6-ylmethyl)-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine
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PubChem ID
CID: 68289353
Canonical SMILES
Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4nccn4n3)c2n1
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Compound Formula C15H12N10
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000450 NCI-H441 Homo sapiens (Human)  1
1
IC50 = 63 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 24 nM