General Information of the Compound
Compound ID
CP0052398
Compound Name
(3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-yl)hexanamide
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Synonyms
(R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamide
348622-88-8
5-[(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl]-1,2,4-oxadiazole-3-carboxamide
5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazole-3-carboxamide
AKOS024458022
ARJCBSRIPGJMAD-LLVKDONJSA-N
BDBM50216795
CHEMBL226630
CS-0414
CTK8F1316
DTXSID30431303
MLS006011234
MolPort-016-633-322
RL03300
SB19579
SCHEMBL6430715
SYN3014
UK 383367
UK-383367
UK383367
ZINC3818556
s2224
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Structure
Formula
C15H24N4O4
Molecular Weight
324.381
Canonical SMILES
NC(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO
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InChI
InChI=1S/C15H24N4O4/c16-13(21)14-17-15(23-19-14)11(9-12(20)18-22)8-4-7-10-5-2-1-3-6-10/h10-11,22H,1-9H2,(H2,16,21)(H,18,20)/t11-/m1/s1
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InChIKey
ARJCBSRIPGJMAD-LLVKDONJSA-N
Physicochemical Property
logP
1.8982
Rotatable Bonds
8
Heavy Atom Count
23
Polar Areas
131.34
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 9818682
SID: 14777196
ChEMBL ID
CHEMBL226630
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01896, Bone morphogenetic protein 1
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 26 nM
Clinical Information about the Compound
Drug 1 ( UK-383367 )
Drug Name UK-383367
Target(s)
Bone morphogenetic protein 1 (BMP1)
 Target Info 
Inhibitor