General Information of the Compound
| Compound ID |
CP0052262
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| Compound Name |
N,N-dimethyl-2-[4-[6-phenyl-7-[4-[[4-(3-pyridin-2-yl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]methyl]phenyl]pyrido[2,3-d]pyrimidin-2-yl]piperazin-1-yl]ethanamine
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| Structure |
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| Formula |
C40H45N11
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| Molecular Weight |
679.877
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| Canonical SMILES |
CN(C)CCN1CCN(CC1)c1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1
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| InChI |
InChI=1S/C40H45N11/c1-48(2)20-21-49-22-24-51(25-23-49)40-42-27-33-26-34(30-8-4-3-5-9-30)36(43-37(33)45-40)31-13-11-29(12-14-31)28-50-18-15-32(16-19-50)38-44-39(47-46-38)35-10-6-7-17-41-35/h3-14,17,26-27,32H,15-16,18-25,28H2,1-2H3,(H,44,46,47)
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| InChIKey |
UGXRNXXGEXPELZ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2
Protein ID: PT00845, RAC-alpha serine/threonine-protein kinase
Protein ID: PT01131, RAC-beta serine/threonine-protein kinase