General Information of the Compound
| Compound ID |
CP0041554
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| Compound Name |
Thyroxine
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| Synonyms |
(-)-Thyroxine
(125I)T4
(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-propanoic acid
3,3',5,5"-Tetraiodo-L-thyronine
3,3',5,5''-Tetraiodo-L-thyronine
3,3',5,5'-Tetraiodo-L-thyronine
3,5,3',5'-Tetraiodo-L-thyronine
3,5,3',5'-Tetraiodothyronine
3,5,3'5'-Tetraiodo-L-thyronine
3-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)alanine
3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine
4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine
Beta-((3,5-Diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl)alanine
DL-Thyroxin
Eltroxin
Eltroxin (TN)
Euthyrox
Euthyrox (TN)
Eutirox (TN)
Forthyron
Forthyron (TN)
L-3,5,3',5'-Tetraiodothyronine
L-Thryoxin
L-Thyroxin
L-thyroxine
L-thyroxine (TN)
LT00440967
Laevothyroxinum
Laevothyroxinum (acid)
Laevoxin
Levaxin (TN)
Levo-T
Levolet
Levothroid
Levothroid (*Sodiumsalt*)
Levothyrox
Levothyroxin
Levothyroxine
Levothyroxine (BAN)
Levothyroxine Sodium (L-thyroxine)
Levothyroxine sodium
Levothyroxinum (acid)
Levoxyl
Levoxyl (TN)
O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
Oroxine
Synthroid
Synthroid (*Sodium salt*)
Synthroid (TN)
Synthroid sodium
T-3850
T4 (Hormone)
T4 levothyroxine
THX
Tetraiodothyronine
Thyratabs
Thyrax
Thyrax (TN)
Thyreoideum
Thyrox (TN)
Thyroxevan
Thyroxin
Thyroxinal
Thyroxine (VAN)
Thyroxine (l)
Thyroxine [BAN]
Thyroxine iodine
Thyroxine, L-(8CI)
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| Structure |
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| Formula |
C15H11I4NO4
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| Molecular Weight |
776.872
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| Canonical SMILES |
[NH3+][C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O
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| InChI |
InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
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| InChIKey |
XUIIKFGFIJCVMT-LBPRGKRZSA-N
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| CAS |
51-48-9
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01552, Nuclear receptor subfamily 1 group I member 2
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Protein ID: PT01930, Retinoic acid receptor RXR-alpha
Protein ID: PT06163, Solute carrier organic anion transporter family member 1A3
Protein ID: PT06337, Solute carrier organic anion transporter family member 4C1
Protein ID: PT02311, UDP-glucuronosyltransferase 1A1
Clinical Information about the Compound