General Information of the Compound
Compound ID
CP0035618
Compound Name
1,4-Dihydroxybenzene, XIII
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Synonyms
1,4-Dihydroxy-benzol
1,4-Dihydroxybenzene
1,4-benzenediol
123-31-9
4-Hydroxyphenol
Accutin
Arctuvin
Artra
Benzene, p-dihydroxy-
Benzene-1,4-diol
Benzohydroquinone
Benzoquinol
Derma-Blanch
Diak 5
Dihydroquinone
Dihydroxybenzene
Eldopaque
Eldopaque Forte
Eldoquin
Eldoquin Forte
Hidroquinone
Hydrochinon
Hydrochinone
Hydroquinole
Hydroquinone
Idrochinone
Phiaquin
Quinol
Solaquin forte
Tecquinol
Tenox HQ
Tequinol
Usaf ek-356
hydroquinol
hydroquinone
p-Benzenediol
p-Dihydroxybenzene
p-Dioxybenzene
p-Hydroquinone
p-Hydroxyphenol
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Structure
Formula
C6H6O2
Molecular Weight
110.112
Canonical SMILES
Oc1ccc(O)cc1
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InChI
InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
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InChIKey
QIGBRXMKCJKVMJ-UHFFFAOYSA-N
CAS
57534-13-1
8027-02-9
123-31-9
Physicochemical Property
logP
1.0978
Rotatable Bonds
0
Heavy Atom Count
8
Polar Areas
40.46
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
8

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 785
SID: 14842848
ChEMBL ID
CHEMBL537
DrugBank ID
DB09526
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480
 Cell Line Info 
Homo sapiens (Human)  1
1
Potency ~ 13953.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001056 MEF-1 [Mouse fibroblast]
 Cell Line Info 
Mus musculus (Mouse)  1
1
Potency = 14689.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( Hydroquinone )
Drug Name Hydroquinone
Indication
Melasma
Approved
Target(s)
Tyrosinase (TYR)
 Target Info 
Inhibitor