General Information of the Compound
| Compound ID |
CP0008940
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| Compound Name |
(R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionic acid
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| Synonyms |
(+-)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
(RS)-AMPA
4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo-
74341-63-2
77521-29-0
AMPA
AMPA (pharmaceutical)
CHEBI:34018
CHEMBL13378
D,L-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
[3H]AMPA
alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
ampa
dl-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
gamma-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid
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| Structure |
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| Formula |
C7H10N2O4
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| Molecular Weight |
186.167
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| Canonical SMILES |
Cc1o[nH]c(=O)c1CC(N)C(O)=O
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| InChI |
InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)
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| InChIKey |
UUDAMDVQRQNNHZ-UHFFFAOYSA-N
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| CAS |
86495-63-8
92614-50-1
110592-37-5
126632-03-9
133481-32-0
139261-99-7
139559-02-7
74341-63-2
77521-29-0
78729-80-3
79697-77-1
81323-87-7
83354-19-2
85506-19-0
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02409, Glutamate receptor 1
Protein ID: PT01414, Glutamate receptor 2
Protein ID: PT03116, Glutamate receptor 3
Protein ID: PT06060, Glutamate receptor 4
Protein ID: PT02200, Glutamate receptor ionotropic, kainate 1
Clinical Information about the Compound