General Information of the Compound
| Compound ID |
CP0008380
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
4-[[5-(4-fluorophenyl)-3-methylpyrazol-1-yl]methyl]-N-hydroxybenzamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C18H16FN3O2
|
||||||||||||||||||
| Molecular Weight |
325.343
|
||||||||||||||||||
| Canonical SMILES |
Cc1cc(-c2ccc(F)cc2)n(Cc2ccc(cc2)C(=O)NO)n1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C18H16FN3O2/c1-12-10-17(14-6-8-16(19)9-7-14)22(20-12)11-13-2-4-15(5-3-13)18(23)21-24/h2-10,24H,11H2,1H3,(H,21,23)
Show/Hide
|
||||||||||||||||||
| InChIKey |
QOKNQGZUAGLUCJ-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT00835, Histone deacetylase 2
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8