| Compound ID |
Compound Name |
Compound Formula |
|
CP0076419
|
(S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-pentanoic acid ((S)-benzyl-cyano-methyl)-amide
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|
C30H32F3N3O3S
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
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CP0243116
|
(S)-4,4-dichloro-N-((S)-1-cyano-2-phenylethyl)-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)butanamide
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|
C28H26Cl2F3N3O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
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CP0255533
|
(S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C31H29F5N4O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0359165
|
(S)-N-((S)-1-cyano-2-(pyridin-4-yl)ethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C29H30F4N4O3S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0076420
|
1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethylamino)-3-methyl-1-oxobutan-2-ylamino)-2,2,2-trifluoroethyl)biphenyl-4-yl)cyclopropanecarboxamide
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|
C33H31F4N5O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0294390
|
(S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(1-(morpholine-4-carbonyl)cyclopropyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C37H40F4N4O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0091658
|
(S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl)-3-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)butanamide
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|
C30H28F4N4O3S
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0294391
|
(S)-2-((S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2,2,2-trifluoroethylamino)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methylpentanamide
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|
C26H27F4N5O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0302971
|
1-(4'-((S)-1-((S)-1-((S)-1-cyano-2-phenylethylamino)-4-fluoro-4-methyl-1-oxopentan-2-ylamino)-2,2,2-trifluoroethyl)biphenyl-4-yl)cyclopropanecarboxamide
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|
C33H34F4N4O2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0243115
|
(S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(pyridin-4-yl)biphenyl-4-yl)ethylamino)pentanamide
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|
C34H32F4N4O
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0105431
|
(S)-N-((S)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl)-2-((S)-1-(4'-((R)-2,2-difluoro-1-hydroxyethyl)biphenyl-4-yl)-2,2,2-trifluoroethylamino)-3-methylbutanamide
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|
C31H28F6N4O2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0076422
|
(S)-N-((S)-1-cyano-2-phenylethyl)-2-((S)-1-(4'-((R)-2,2-difluoro-1-hydroxyethyl)biphenyl-4-yl)-2,2,2-trifluoroethylamino)-4-fluoro-4-methylpentanamide
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|
C31H31F6N3O2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0076418
|
(S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C30H31F4N3O3S
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0345241
|
(S)-N-((R)-1-cyano-2-(4-cyano-2-fluorophenyl)ethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C31H29F5N4O3S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0105430
|
(S)-N-((S)-1-cyano-2-phenylethyl)-2-cyclopropyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)acetamide
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|
C29H28F3N3O3S
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0294392
|
(S)-N-((S)-1-cyano-2-phenylethyl)-3-cyclopropyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)propanamide
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|
C30H30F3N3O3S
|
1
|
| 1 |
IC50 = 147 nM
|
|
|
|
CP0105429
|
(S)-N-((S)-1-cyano-2-phenylethyl)-3-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)butanamide
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|
C29H30F3N3O3S
|
1
|
| 1 |
IC50 = 174 nM
|
|
|
|
CP0340558
|
(S)-N-(cyanomethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C23H25F4N3O3S
|
1
|
| 1 |
IC50 = 547 nM
|
|
|
|
CP0076421
|
(S)-N-((S)-1-cyano-3,3,3-trifluoropropyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C25H26F7N3O3S
|
1
|
| 1 |
IC50 = 654 nM
|
|
|
|
CP0243122
|
(S)-N-((S)-1-cyano-2-phenylethyl)-3-phenyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)propanamide
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|
C33H30F3N3O3S
|
1
|
| 1 |
IC50 = 769 nM
|
|
|
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CP0243114
|
(S)-N-((S)-1-cyano-3-phenylpropyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C31H33F4N3O3S
|
1
|
| 1 |
IC50 = 3242 nM
|
|
|
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CP0091657
|
(S)-N-((S)-cyano(1-phenylcyclopropyl)methyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanamide
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|
C32H33F4N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0350672
|
(S)-N-((S)-1-cyano-2-phenylethyl)-3,3-dimethyl-2-((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)butanamide
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|
C30H32F3N3O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
