General Information of the Cell Line
Cell Line ID
CL000950
Cell Line Name
GIST882
Synonyms
GIST-882
GIST 882
Category
Cancer cell line
Organism
Homo sapiens (Human)
Disease
Gastrointestinal stromal tumor (NCIt: C3868)
Gastrointestinal stromal tumor (ORDO: Orphanet_44890)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
 Protein Info 
Compound ID Compound Name Compound Formula
CP0639448
 Compound Info 
Imatinib mesilate
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C30H35N7O4S
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0690323
 Compound Info 
N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(6,7-dimethoxy-9H-pyrimido[4,5-b]indol-4-yl)piperazine-1-carbothioamide
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C25H26N6O4S
  1
1
IC50 = 450 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0085333
 Compound Info 
Amuvatinib
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C23H21N5O3S
  1
1
IC50 = 1600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0006232
 Compound Info 
4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid (benzo[1,3]dioxol-5-ylmethyl)-amide
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C23H25N5O4S
  1
1
IC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0888243
 Compound Info 
4-(benzofuro[3,2-d]pyrimidin-4-yl)-N-(4-(N-pyrimidin-2-ylsulfamoyl)phenyl)piperazine-1-carbothioamide
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C25H22N8O3S2
  1
1
IC50 = 27500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0173802
 Compound Info 
4-(6,7-Dimethoxy-9H-pyrimido[4,5-b]indol-4-yl)-piperazine-1-carbothioic acid [4-(pyrimidin-2-ylsulfamoyl)-phenyl]-amide
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C27H27N9O4S2
  1
1
IC50 = 28000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0881758
 Compound Info 
4-Pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl-piperazine-1-carbothioic acid(benzo[1,3]dioxol-5-ylmethyl)-amide
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C22H20N6O2S2
  1
1
IC50 = 28000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0888241
 Compound Info 
4-(6,7-dimethoxyquinazolin-4-yl)-N-(4-(N-pyrimidin-2-ylsulfamoyl)phenyl)piperazine-1-carbothioamide
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C25H26N8O4S2
  1
1
IC50 = 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0895676
 Compound Info 
4-Pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl-piperazine-1-carbothioic acid [4-(pyrimidin-2-ylsulfamoyl)-phenyl]-amide
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C24H21N9O2S3
  1
1
IC50 = 50000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0135795
 Compound Info 
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
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 C25H29N9O2S  1
1
GI50 = 3 nM
   TI
   LI
   LO
   TS
CP0416039
 Compound Info 
N-(3-fluorophenyl)-N'-[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]propanediamide
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 C23H18FN5O2  1
1
GI50 = 296 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line