Brief Information of the Compound and Protein
Compound Name
4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid (benzo[1,3]dioxol-5-ylmethyl)-amide
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PubChem ID
CID: 9890746
SID: 14858448
Canonical SMILES
COc1cc2ncnc(N3CCN(CC3)C(=S)NCc3ccc4OCOc4c3)c2cc1OC
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Compound Formula C23H25N5O4S
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000950 GIST882 Homo sapiens (Human)  1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 220 nM