Brief Information of the Compound and Protein
Compound Name
4-(benzofuro[3,2-d]pyrimidin-4-yl)-N-(4-(N-pyrimidin-2-ylsulfamoyl)phenyl)piperazine-1-carbothioamide
    Show/Hide
PubChem ID
CID: 11753137
SID: 16860811
Canonical SMILES
O=S(=O)(Nc1ncccn1)c1ccc(NC(=S)N2CCN(c3ncnc4c3oc3ccccc34)CC2)cc1
    Show/Hide
Compound Formula C25H22N8O3S2
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000950 GIST882 Homo sapiens (Human)  1
1
IC50 = 27500 nM
   TI
   LI
   LO
   TS