General Information of the Cell Line
Cell Line ID
CL000627
Cell Line Name
OE19
Synonyms
OE-19
JROECL 19
JROECL19
OEC19
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1622
Tissue Information
Esophagus
Disease
Esophageal adenocarcinoma (NCIt: C4025)
Adenocarcinoma of the esophagus (ORDO: Orphanet_99976)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT07254, Ceramide UDP-galactosyltransferase
 Protein Info 
Compound ID Compound Name Compound Formula
CP0354711
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] N-[(2S)-1-(trifluoromethoxy)propan-2-yl]carbamate
   Show/Hide
C20H22F6N4O4S
  1
1
IC50 = 0.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552773
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] N-[2-(trifluoromethoxy)ethyl]carbamate
   Show/Hide
C19H20F6N4O4S
  2
1
IC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 0.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555876
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] N-[(2S)-butan-2-yl]carbamate
   Show/Hide
C20H25F3N4O3S
  2
1
IC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 0.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0562674
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] N-[(1S)-1-cyclopropylethyl]carbamate
   Show/Hide
C21H25F3N4O3S
  2
1
IC50 = 0.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555877
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] N-(cyclopropylmethyl)carbamate
   Show/Hide
C20H23F3N4O3S
  2
1
IC50 = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0540469
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] 3-(trifluoromethoxy)azetidine-1-carboxylate
   Show/Hide
C20H20F6N4O4S
  2
1
IC50 = 1.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 2.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0511908
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] N-propan-2-ylcarbamate
   Show/Hide
C19H23F3N4O3S
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0531870
 Compound Info 
cyclopropylmethyl N-[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl]carbamate
   Show/Hide
C20H23F3N4O3S
  2
1
IC50 = 18 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 37 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0514894
 Compound Info 
cyclopropylmethyl N-[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]azetidin-3-yl]carbamate
   Show/Hide
C18H19F3N4O3S
  2
1
IC50 = 43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 48 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0565776
 Compound Info 
N-methyl-5-[4-[2-oxo-2-(propan-2-ylamino)ethyl]piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxamide
   Show/Hide
C19H24F3N5O2S
  2
1
IC50 = 67 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 90 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0487545
 Compound Info 
2-[4-[3-propanoyl-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperazin-1-yl]-N-propan-2-ylacetamide
   Show/Hide
C20H25F3N4O2S
  2
1
IC50 = 97 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0561735
 Compound Info 
5-[4-[1-(cyclopropylamino)-1-oxopropan-2-yl]piperazin-1-yl]-N-methyl-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxamide
   Show/Hide
C20H24F3N5O2S
  2
1
IC50 = 170 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 360 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555874
 Compound Info 
5-[4-[2-hydroxy-3-[(2-methylpropan-2-yl)oxy]propyl]piperazin-1-yl]-N-methyl-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxamide
   Show/Hide
C21H29F3N4O3S
  2
1
IC50 = 190 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 350 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555875
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]azetidin-3-yl] N-(cyclopropylmethyl)carbamate
   Show/Hide
C18H19F3N4O3S
  1
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0487546
 Compound Info 
N-methyl-5-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxamide
   Show/Hide
C19H25F3N4O2S
  2
1
IC50 = 200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0511907
 Compound Info 
2-[4-[3-(azetidine-1-carbonyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperazin-1-yl]-N-propan-2-ylacetamide
   Show/Hide
C21H26F3N5O2S
  2
1
IC50 = 320 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 640 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0555873
 Compound Info 
N-methyl-5-[4-(2-propan-2-yloxyacetyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxamide
   Show/Hide
C19H23F3N4O3S
  2
1
IC50 = 450 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 660 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552573
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] N-(2-pyrrolidin-1-ylethyl)carbamate
   Show/Hide
C22H28F3N5O3S
  1
1
IC50 = 510 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0511909
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]pyrrolidin-3-yl] N-(cyclopropylmethyl)carbamate
   Show/Hide
C19H21F3N4O3S
  1
1
IC50 = 610 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0560746
 Compound Info 
5-[4-(3,3-dimethyl-2-oxobutyl)piperazin-1-yl]-N-methyl-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxamide
   Show/Hide
C20H25F3N4O2S
  2
1
IC50 = 610 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0573323
 Compound Info 
[1-[3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl]piperidin-4-yl] 3-[(dimethylamino)methyl]azetidine-1-carboxylate
   Show/Hide
C22H28F3N5O3S
  1
1
IC50 = 980 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0003832
 Compound Info 
N'-hydroxy-N-phenyloctanediamide
   Show/Hide
 C14H20N2O3  1
1
GI50 = 1420 nM
   TI
   LI
   LO
   TS
CP0011692
 Compound Info 
N-(2-aminophenyl)-4-[[[2-(benzylamino)-2-oxoethyl]-[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]methyl]benzamide
   Show/Hide
 C35H35N5O4S  1
1
GI50 = 9100 nM
   TI
   LI
   LO
   TS
CP0013516
 Compound Info 
6-[[2-(benzylamino)-2-oxoethyl]-[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]-N-hydroxyhexanamide
   Show/Hide
 C27H34N4O5S  1
1
GI50 = 925 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Esophagus)
Cell Line Name Organism Disease
OE33
 Cell Line Info 
Homo sapiens (Human) Barrett adenocarcinoma
SK-GT-4
 Cell Line Info 
Homo sapiens (Human) Esophageal adenocarcinoma
KYSE-150
 Cell Line Info 
Homo sapiens (Human) Esophageal squamous cell carcinoma
KYSE-520
 Cell Line Info 
Homo sapiens (Human) Esophageal squamous cell carcinoma