Brief Information of the Cell Line and Protein
Cell Line ID: CL000778 , SF-12
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Protein ID: PT00967 , Glucocorticoid receptor
Gene Name NR3C1
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P04150
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000778  Protein ID: PT00967
 
Compound ID Compound Name Compound Formula
CP0041416
(6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione
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C24H34O4
 1
1
Ki = 13.2 nM
   TI
   LI
   LO
   TS
CP0038813
(1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
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C21H30O2
 1
1
Ki = 30.5 nM
   TI
   LI
   LO
   TS
CP0088155
9-Fluoro-2,2,4-trimethyl-5-[1-thiophen-3-yl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C24H20FNOS
 1
1
Ki = 84 nM
   TI
   LI
   LO
   TS
CP0100985
9-Fluoro-5-[1-furan-2-yl-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C24H20FNO2
 1
1
Ki = 140 nM
   TI
   LI
   LO
   TS
CP0134269
5-[1-(2,5-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C26H21F2NO
 1
1
Ki = 173 nM
   TI
   LI
   LO
   TS
CP0301665
5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C26H22FNO
 1
1
Ki = 180 nM
   TI
   LI
   LO
   TS
CP0200504
9-Fluoro-2,2,4-trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C26H22FNO
 1
1
Ki = 207 nM
   TI
   LI
   LO
   TS
CP0063848
7-Fluoro-2,2,4-trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C27H24FNO
 1
1
Ki = 232 nM
   TI
   LI
   LO
   TS
CP0063871
9-Fluoro-2,2,4-trimethyl-5-[1-(3-methyl-pyridin-4-yl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C26H23FN2O
 1
1
Ki = 232 nM
   TI
   LI
   LO
   TS
CP0182597
9-Fluoro-2,2,4-trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C27H24FNO
 1
1
Ki = 236 nM
   TI
   LI
   LO
   TS
CP0146748
5-[1-(3,4-Difluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C26H21F2NO
 1
1
Ki = 237 nM
   TI
   LI
   LO
   TS
CP0101021
5-[1-(2-Ethyl-phenyl)-meth-(Z)-ylidene]-9-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C28H26FNO
 1
1
Ki = 270 nM
   TI
   LI
   LO
   TS
CP0185600
9-Fluoro-5-[1-(2-methoxy-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C27H24FNO2
 1
1
Ki = 277 nM
   TI
   LI
   LO
   TS
CP0193631
2,2,4-Trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C26H23NO
 1
1
Ki = 299 nM
   TI
   LI
   LO
   TS
CP0162846
7-Fluoro-2,2,4-trimethyl-5-[1-phenyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C26H22FNO
 1
1
Ki = 321 nM
   TI
   LI
   LO
   TS
CP0185170
9-Fluoro-2,2,4-trimethyl-5-[1-(2-methylsulfanyl-phenyl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C27H24FNOS
 1
1
Ki = 386 nM
   TI
   LI
   LO
   TS
CP0112566
2-[(Z)-(9-fluoro-2,2,4-trimethyl-1H-chromeno[3,4-f]quinolin-5-ylidene)methyl]-N,N-dimethylaniline
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C28H27FN2O
 1
1
Ki = 493 nM
   TI
   LI
   LO
   TS
CP0104425
2,2,4-Trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C27H25NO
 1
1
Ki = 564 nM
   TI
   LI
   LO
   TS
CP0185145
9-Fluoro-2,2,4-trimethyl-5-[1-(3-methyl-pyridin-2-yl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene
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C26H23FN2O
 1
1
Ki = 874 nM
   TI
   LI
   LO
   TS