Brief Information of the Cell Line and Protein
Cell Line ID: CL000749 , HUVEC-C
Synonyms
HUV-EC-C
HUVEC
Category Finite cell line
Organism
Homo sapiens (Human)
Protein ID: PT01982 , Endothelin-converting enzyme 1
Gene Name ECE1
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P42892
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000749  Protein ID: PT01982
 
Compound ID Compound Name Compound Formula
CP0475631
2-[(2-{[hydroxy(4-phenyl-butyl)phosphoryl]amino}-3-phenyl-propanoyl)amino]-3-(1H-indol-3-yl)propanoic acid
   Show/Hide
C30H34N3O5P
 1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
CP0044595
(3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-2H-pyran-2-yl hydrogen (S)-1-((S)-1-(1H-indol-3-yl)-3-oxobutan-2-ylamino)-4-methyl-1-oxopentan-2-ylphosphoramidate
   Show/Hide
C23H34N3O10P
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0480745
2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-methyl-pentanoic acid
   Show/Hide
C32H39N2O7P
 1
1
IC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0374939
2-{(R)-2-Benzyl-3-[(1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-5-guanidino-pentanoic acid
   Show/Hide
C32H40N5O7P
 1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS
CP0930750
2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-hydroxy-butyric acid
   Show/Hide
C30H35N2O8P
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0372390
2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-propionic acid
   Show/Hide
C29H33N2O7P
 1
1
IC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0464192
2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-phenyl-propionic acid
   Show/Hide
C35H37N2O7P
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0372332
2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-hexanoic acid
   Show/Hide
C32H39N2O7P
 1
1
IC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0404567
2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-succinamic acid
   Show/Hide
C30H34N3O8P
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0463550
2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-(1H-imidazol-4-yl)-propionic acid
   Show/Hide
C32H35N4O7P
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0466763
((R)-1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-((S)-1-carbamoyl-2-methyl-propylcarbamoyl)-3-phenyl-propyl]-phosphinic acid
   Show/Hide
C31H38N3O6P
 1
1
IC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0490330
2-[[2-benzyl-3-[hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]propanoyl]amino]pentanedioic acid
   Show/Hide
C31H35N2O9P
 1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS
CP0403720
2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-succinic acid
   Show/Hide
C30H33N2O9P
 1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0510261
3-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-propionic acid
   Show/Hide
C29H33N2O7P
 1
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
CP0480712
2-[[2-benzyl-3-[hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]propanoyl]amino]acetic acid
   Show/Hide
C28H31N2O7P
 1
1
IC50 = 80000 nM
   TI
   LI
   LO
   TS
CP0372333
(2R,3S)-2-[[2-benzyl-3-[hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]propanoyl]amino]-3-hydroxybutanoic acid
   Show/Hide
C30H35N2O8P
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0430490
(R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-5-guanidino-pentanoic acid
   Show/Hide
C32H40N5O7P
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0439011
(R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-pentanedioic acid
   Show/Hide
C31H35N2O9P
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0480613
(R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-propionylamino}-3-phenyl-propionic acid
   Show/Hide
C35H37N2O7P
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS