| Compound ID |
Compound Name |
Compound Formula |
|
CP0568849
|
N-[(1R)-1-cyclohexyl-2-(3-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-2-oxoethyl]-2-fluoro-3-methylbenzamide
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|
C30H37FN4O3
|
2
|
| 1 |
IC50 = 1.6 nM
|
|
|
| 2 |
IC50 = 56 nM
|
|
|
|
CP0402340
|
3-methyl-N-[(2R)-3-methyl-1-(3-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxobutan-2-yl]benzamide
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|
C27H34N4O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0487590
|
N-[(1R)-1-cyclohexyl-2-[3-[2-(methylamino)-2-oxoethyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl]-2-oxoethyl]-2-fluoro-3-methylbenzamide
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|
C32H40FN5O4
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 86 nM
|
|
|
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CP0473075
|
3-fluoro-N-[(2R)-3-methyl-1-(3-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxobutan-2-yl]benzamide
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|
C26H31FN4O3
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0402339
|
3-chloro-N-[(1R)-1-cyclohexyl-2-[3-[2-(methylamino)-2-oxoethyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl]-2-oxoethyl]benzamide
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|
C31H38ClN5O4
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0964844
|
(R)-N-(1-(1-(1H-Indazol-5-yl)-3-methyl-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-2-fluoro-5-(trifluoromethyl)benzamide
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|
C28H30F4N6O3
|
1
|
| 1 |
IC50 = 13.4 nM
|
|
|
|
CP0558161
|
(R)-4-(8-(2-(2-Fluoro-5-(trifluoromethyl)benzamido)-3-methylbutanoyl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-1-yl)benzoic Acid
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|
C28H28F4N4O6
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0964843
|
(R)-N-(2-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-cyclopentyl-2-oxoethyl)-2-fluoro-5-(trifluoromethyl)benzamide
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|
C30H30F4N6O4
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0437800
|
(R)-2-Fluoro-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-p-tolyl-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxobutan-2-yl)-5-(trifluoromethyl)benzamide
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|
C28H30F4N4O4
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0549366
|
(R)—N-(1-(1-(3-Chlorophenyl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-2-fluoro-5-(trifluoromethyl)benzamide
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|
C27H27ClF4N4O4
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0664932
|
(R)-N-(1-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-2-fluoro-5-(trifluoromethyl)benzamide
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|
C28H28F4N6O4
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0402341
|
(R)-2-Fluoro-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxobutan-2-yl)-5-(trifluoromethyl)benzamide
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|
C27H28F4N4O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0947856
|
(R)-N-(1-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-3-(trifluoromethyl)benzamide
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|
C28H29F3N6O4
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0548344
|
N-[(1R)-1-cyclohexyl-2-[3-[2-(methylamino)-2-oxoethyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl]-2-oxoethyl]benzamide
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|
C31H39N5O4
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0549365
|
(R)-3-Methyl-N-(2-(3-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)benzamide
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|
C29H36N4O4
|
1
|
| 1 |
IC50 = 623 nM
|
|
|
|
CP0386968
|
(R)-2-Fluoro-3-methyl-N-(3-methyl-1-(3-methyl-2,4-dioxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxobutan-2-yl)benzamide
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|
C27H31FN4O4
|
1
|
| 1 |
IC50 = 683 nM
|
|
|
|
CP0414345
|
N-[(1R)-1-cyclohexyl-2-(1-cyclopropyl-3-methyl-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)-2-oxoethyl]-2-fluoro-3-methylbenzamide
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|
C27H37FN4O3
|
1
|
| 1 |
IC50 = 819 nM
|
|
|
|
CP0548345
|
N-[(1R)-1-cyclohexyl-2-(3-methyl-4-oxo-1-pyridin-2-yl-1,3,8-triazaspiro[4.5]decan-8-yl)-2-oxoethyl]-3-methylbenzamide
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|
C29H37N5O3
|
1
|
| 1 |
IC50 = 905 nM
|
|
|
|
CP0912042
|
(R)-N-(1-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-2-chloro-5-(trifluoromethyl)benzamide
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|
C28H28ClF3N6O4
|
1
|
| 1 |
IC50 = 1470 nM
|
|
|
|
CP0928401
|
(R)-N-(1-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-2-methyl-5-(trifluoromethyl)benzamide
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|
C29H31F3N6O4
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0409279
|
N-(2-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-2-oxoethyl)-2-fluoro-5-(trifluoromethyl)benzamide
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|
C25H22F4N6O4
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0487577
|
(S)-3-Methyl-N-(2-(3-methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)benzamide
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|
C29H36N4O4
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0953708
|
(S)-N-(1-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-2-fluoro-5-(trifluoromethyl)benzamide
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|
C28H28F4N6O4
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
