Brief Information of the Cell Line and Protein
Cell Line ID: CL000559 , KMS-11
 Cell Line Info 
Synonyms
KMS11
kms11
kms 11
Kawasaki Medical School-11
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_2989
Protein ID: PT01699 , G protein-coupled receptor kinase 6
 Protein Info 
Gene Name GRK6
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P43250
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000559
 Cell Line Info 
 Protein ID: PT01699
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0131253
 Compound Info 
2-N-[(4-chloro-2-methoxyphenyl)methyl]-4-N-(5-ethyl-1H-pyrazol-3-yl)-5-methoxyquinazoline-2,4-diamine
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C22H23ClN6O2
  1
1
IC50 = 30 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552988
 Compound Info 
2-N-[(4-chloro-2-methoxyphenyl)methyl]-4-N-(5-ethyl-1H-pyrazol-3-yl)-5-methylquinazoline-2,4-diamine
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C22H23ClN6O
  1
1
IC50 = 170 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0835612
 Compound Info 
(S)-N4-(3-Ethyl-1H-pyrazol-5-yl)-N2-(1-(5-fluoropyridin-2-yl)-ethyl)-5-methylquinazoline-2,4-diamine
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C21H22FN7
  1
1
IC50 = 610 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0267013
 Compound Info 
2-N-[(4-chlorophenyl)methyl]-4-N-(5-ethyl-1H-pyrazol-3-yl)-5-methoxyquinazoline-2,4-diamine
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C21H21ClN6O
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0773120
 Compound Info 
(S)-N4-(5-ethyl-1H-pyrazol-3-yl)-N2-(1-(5-fluoropyridin-2-yl)ethyl)-5-methoxyquinazoline-2,4-diamine
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C21H22FN7O
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0131252
 Compound Info 
4-N-(5-ethyl-1H-pyrazol-3-yl)-2-N-[(5-fluoropyridin-2-yl)methyl]-5-methoxyquinazoline-2,4-diamine
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C20H20FN7O
  1
1
IC50 = 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS