| Compound ID |
Compound Name |
Compound Formula |
|
CP0253603
|
2-((R)-1-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)pyrrolidin-2-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)acetamide
Show/Hide
|
C22H24N6O3
|
1
|
| 1 |
IC50 = 0.12 nM
|
|
|
|
CP0433712
|
2-((R)-1-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)pyrrolidin-2-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)acetamide
Show/Hide
|
C23H26N6O3
|
1
|
| 1 |
IC50 = 0.13 nM
|
|
|
|
CP0141015
|
(3S)-methyl 4-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)-3-(2-(benzo[d][1,3]dioxol-5-ylmethylamino)-2-oxoethyl)piperazine-1-carboxylate
Show/Hide
|
C23H25N7O5
|
1
|
| 1 |
IC50 = 0.24 nM
|
|
|
|
CP0173101
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(6-fluoropyridin-2-yl)-1-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C26H25FN8O3
|
1
|
| 1 |
IC50 = 0.28 nM
|
|
|
|
CP0343979
|
2-((R)-1-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)pyrrolidin-2-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)acetamide
Show/Hide
|
C21H22N6O3
|
1
|
| 1 |
IC50 = 0.28 nM
|
|
|
|
CP0518084
|
(2R)-1-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)-N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C22H24N6O3
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
|
CP0161026
|
3-{[(Benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-methyl}-4-(2-imidazol-1-yl-pyrimidin-4-yl)-piperazine-1-carboxylic acid methyl ester
Show/Hide
|
C23H25N7O5
|
1
|
| 1 |
IC50 = 0.38 nM
|
|
|
|
CP0132453
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)-4-methylpiperazin-2-yl]acetamide
Show/Hide
|
C22H25N7O3
|
1
|
| 1 |
IC50 = 0.48 nM
|
|
|
|
CP0284965
|
2-((R)-1-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)pyrrolidin-2-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)acetamide
Show/Hide
|
C21H22N6O3
|
1
|
| 1 |
IC50 = 0.48 nM
|
|
|
|
CP0141014
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(6-chloro-2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C22H23ClN6O3
|
1
|
| 1 |
IC50 = 0.49 nM
|
|
|
|
CP0047859
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(2-imidazol-1-ylpyrimidin-4-yl)morpholin-3-yl]acetamide
Show/Hide
|
C21H22N6O4
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0140723
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)-4-(2-phenylmethoxyacetyl)piperazin-2-yl]acetamide
Show/Hide
|
C30H31N7O5
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0284950
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-benzoyl-1-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C28H27N7O4
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0335689
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C22H24N6O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0051686
|
(2R)-N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-1-(6-ethyl-2-(1H-imidazol-1-yl)pyrimidin-4-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C23H26N6O3
|
1
|
| 1 |
IC50 = 0.52 nM
|
|
|
|
CP0285271
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C21H23N7O3
|
1
|
| 1 |
IC50 = 0.55 nM
|
|
|
|
CP0347950
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(furan-2-ylmethyl)-1-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C26H27N7O4
|
1
|
| 1 |
IC50 = 0.58 nM
|
|
|
|
CP0455596
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(furan-2-carbonyl)-1-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C26H25N7O5
|
1
|
| 1 |
IC50 = 0.67 nM
|
|
|
|
CP0048093
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)-4-methylsulfonylpiperazin-2-yl]acetamide
Show/Hide
|
C22H25N7O5S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0343980
|
2-((R)-4-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)-1-isobutyrylpiperazin-2-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)acetamide
Show/Hide
|
C26H31N7O4
|
1
|
| 1 |
IC50 = 0.75 nM
|
|
|
|
CP0161027
|
benzyl 3-[2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl]-4-(2-imidazol-1-ylpyrimidin-4-yl)piperazine-1-carboxylate
Show/Hide
|
C29H29N7O5
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0173100
|
1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[(4-methoxyphenyl-)methyl]-2-piperidineacetamide
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0285272
|
3-[2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl]-4-(2-imidazol-1-ylpyrimidin-4-yl)-N-phenylpiperazine-1-carboxamide
Show/Hide
|
C28H28N8O4
|
1
|
| 1 |
IC50 = 0.87 nM
|
|
|
|
CP0543795
|
ethyl 2-[3-[2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl]-4-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-1-yl]acetate
Show/Hide
|
C25H29N7O5
|
1
|
| 1 |
IC50 = 0.93 nM
|
|
|
|
CP0432698
|
3-[2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl]-N-benzyl-4-(2-imidazol-1-ylpyrimidin-4-yl)piperazine-1-carboxamide
Show/Hide
|
C29H30N8O4
|
1
|
| 1 |
IC50 = 0.96 nM
|
|
|
|
CP0048095
|
3-[2-[(1,3-benzodioxol-5-ylmethyl)amino]-2-oxoethyl]-4-[2-(1H-imidazolyl)-4-pyrimidinyl]-1-piperazinecarboxylic Acid, 1-methyl ethyl ester
Show/Hide
|
C25H29N7O5
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0112693
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-benzyl-1-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C28H29N7O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0254956
|
4-(acetyl)-N-[(1,3-benzodioxol-5-yl)methyl]-1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-2-piperazineacetamide
Show/Hide
|
C23H25N7O4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0455597
|
3-[2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl]-4-(2-imidazol-1-ylpyrimidin-4-yl)-N-methylpiperazine-1-carboxamide
Show/Hide
|
C23H26N8O4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0524408
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)-4-(3-methylbutyl)piperazin-2-yl]acetamide
Show/Hide
|
C26H33N7O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0342014
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-[5-(dimethylamino)naphthalen-1-yl]sulfonyl-1-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C33H34N8O5S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0075748
|
3-[2-[(1,3-benzodioxol-5-ylmethyl)amino]-2-oxoethyl]-4-[2-(1H-imidazolyl)-4-pyrimidinyl]-1-piperazinecarboxylic acid, phenyl ester
Show/Hide
|
C28H27N7O5
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0112691
|
1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-N-[(3,4-dimethoxyphenyl)methyl]-2-piperidineacetamide
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0156645
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)-1-(2-methylpropanoyl)piperazin-2-yl]acetamide
Show/Hide
|
C26H31N7O4
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0335690
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)azepan-2-yl]acetamide
Show/Hide
|
C23H26N6O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0363429
|
2-[4-(benzenesulfonyl)-1-(2-imidazol-1-ylpyrimidin-4-yl)piperazin-2-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
Show/Hide
|
C27H27N7O5S
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0112692
|
N-[(4-fluorophenyl)methyl]-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C21H23FN6O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0212638
|
1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[2-(4-methoxyphenyl)ethyl]-2-piperidineacetamide
Show/Hide
|
C23H28N6O2
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0062479
|
1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-N-[(3-methoxyphenyl-)methyl]-2-piperidineacetamide
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0253598
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C23H26N6O3
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0363152
|
2-[2-[(1,3-benzodioxol-5-ylmethyl)amino]-2-oxoethyl]-4-[2-(1H-imidazol-1-yl)-6-methyl-4-pyrimidinyl]-1-piperazinecarboxylic acid, methyl ester
Show/Hide
|
C24H27N7O5
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0492923
|
N-[(4-chlorophenyl)methyl]-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C21H23ClN6O
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0051688
|
2-[1-acetyl-4-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)piperazin-2-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
Show/Hide
|
C24H27N7O4
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0051684
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(6-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C22H24N6O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0215281
|
N-(1H-benzimidazol-2-yl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C21H22N8O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0141017
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)-1-methylpiperazin-2-yl]acetamide
Show/Hide
|
C23H27N7O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0215280
|
1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-piperidineacetamide
Show/Hide
|
C24H30N6O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0343981
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)-1-methylsulfonylpiperazin-2-yl]acetamide
Show/Hide
|
C23H27N7O5S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0155069
|
1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[[4-(methylsulfonyl)-phenyl]methyl]-2-piperidineacetamide
Show/Hide
|
C22H26N6O3S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0274992
|
1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[[4-(trifluoromethoxy)phenyl]methyl]-2-piperidineacetamide
Show/Hide
|
C22H23F3N6O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0486193
|
4-(benzo[d][1,3]dioxol-5-yloxy)-2-(2-chloro-4-(1H-imidazol-1-yl)phenoxy)-6-methylpyrimidine
Show/Hide
|
C21H15ClN4O4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0446151
|
1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-N-[(4-methylphenyl)-methyl]-2-piperidineacetamide
Show/Hide
|
C22H26N6O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0132452
|
1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-N-(phenylmethyl)-2-piperidineacetamide
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0141016
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-benzyl-4-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C29H31N7O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0215279
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)-4-(methyliminomethyl)piperazin-2-yl]acetamide
Show/Hide
|
C23H26N8O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0155070
|
(3R)-methyl 4-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)-3-(2-(benzo[d][1,3]dioxol-5-ylmethylamino)-2-oxoethyl)piperazine-1-carboxylate
Show/Hide
|
C23H25N7O5
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0363151
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-[2,6-di(imidazol-1-yl)pyrimidin-4-yl]piperidin-2-yl]acetamide
Show/Hide
|
C25H26N8O3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0291329
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(4-imidazol-1-ylpyrimidin-2-yl)piperidin-2-yl]acetamide
Show/Hide
|
C22H24N6O3
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0434112
|
2-(4-(1H-imidazol-1-yl)phenoxy)-4-(benzo[d][1,3]dioxol-5-yloxy)pyrimidine
Show/Hide
|
C20H14N4O4
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0253601
|
1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[(2-furanyl)methyl]-2-piperidineacetamide
Show/Hide
|
C19H22N6O2
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0155067
|
N-(3,4-dimethoxyphenyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C22H26N6O3
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0524411
|
N-[[4-(dimethylamino)phenyl]methyl]-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C23H29N7O
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0343977
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-yl-6-phenylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C28H28N6O3
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0360980
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)-4-(naphthalen-1-ylmethyl)piperazin-2-yl]acetamide
Show/Hide
|
C32H31N7O3
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0406529
|
4-(4-(1H-imidazol-1-yl)phenoxy)-2-(benzo[d][1,3]dioxol-5-yloxy)pyrimidine
Show/Hide
|
C20H14N4O4
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0352395
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[1-(3-imidazol-1-ylphenyl)piperidin-2-yl]acetamide
Show/Hide
|
C24H26N4O3
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0486195
|
2-(4-(1H-imidazol-1-yl)phenoxy)-6-(benzo[d][1,3]dioxol-5-yloxy)pyridine
Show/Hide
|
C21H15N3O4
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0486196
|
2-(4-(1H-imidazol-1-yl)phenoxy)-4-(benzo[d][1,3]dioxol-5-yloxy)-6-methylpyrimidine
Show/Hide
|
C21H16N4O4
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0493061
|
4-(benzo[d][1,3]dioxol-5-yloxy)-2-(2-fluoro-4-(1H-imidazol-1-yl)phenoxy)-6-methylpyrimidine
Show/Hide
|
C21H15FN4O4
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0339839
|
N-(1,3-benzodioxol-5-ylmethyl)-2-[4-(2-imidazol-1-yl-6-methylpyrimidin-4-yl)piperazin-2-yl]acetamide
Show/Hide
|
C22H25N7O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0406528
|
2-(4-(1H-imidazol-1-yl)phenoxy)-4-(benzo[d][1,3]dioxol-5-yloxy)-5-methylpyrimidine
Show/Hide
|
C21H16N4O4
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0343978
|
1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[[4-(trifluoromethyl)phenyl]methyl]-2-piperidineacetamide
Show/Hide
|
C22H23F3N6O
|
1
|
| 1 |
IC50 = 150 nM
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CP0215283
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1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-N-[(4-nitrophenyl)-methyl]-2-piperidineacetamide
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C21H23N7O3
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1
|
| 1 |
IC50 = 168 nM
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CP0284963
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N-(1,3-benzodioxol-5-ylmethyl)-2-[1-[2-imidazol-1-yl-6-(trifluoromethyl)pyrimidin-4-yl]piperidin-2-yl]acetamide
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C23H23F3N6O3
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1
|
| 1 |
IC50 = 180 nM
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CP0434111
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6-(4-(1H-imidazol-1-yl)phenoxy)-2-(benzo[d][1,3]dioxol-5-ylmethyl)-N-(3-(dimethylamino)propyl)-N-methylpyrimidin-4-amine
Show/Hide
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C27H30N6O3
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1
|
| 1 |
IC50 = 220 nM
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CP0500968
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2-(4-(1H-imidazol-1-yl)-2-(trifluoromethyl)phenoxy)-4-(benzo[d][1,3]dioxol-5-yloxy)-6-methylpyrimidine
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C22H15F3N4O4
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1
|
| 1 |
IC50 = 220 nM
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|
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CP0446150
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N-[(4-aminophenyl)methyl]-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
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C21H25N7O
|
1
|
| 1 |
IC50 = 270 nM
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|
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CP0285270
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1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-N-[(2-methoxyphenyl-)methyl]-2-piperidineacetamide
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C22H26N6O2
|
1
|
| 1 |
IC50 = 283 nM
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|
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CP0156644
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2-((S)-4-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)-1-isobutyrylpiperazin-2-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)acetamide
Show/Hide
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C26H31N7O4
|
1
|
| 1 |
IC50 = 300 nM
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|
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CP0511119
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2-(4-(1H-imidazol-1-yl)phenoxy)-6-(benzo[d][1,3]dioxol-5-yloxy)-3,5-difluoro-4-methylpyridine
Show/Hide
|
C22H15F2N3O4
|
1
|
| 1 |
IC50 = 450 nM
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|
|
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CP0284964
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1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[(2-pyridinyl)methyl]-2-piperidineacetamide
Show/Hide
|
C20H23N7O
|
1
|
| 1 |
IC50 = 539 nM
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|
|
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CP0498326
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4-(4-(1H-imidazol-1-yl)phenoxy)-2-(benzo[d][1,3]dioxol-5-ylmethyl)-6-morpholinopyrimidine
Show/Hide
|
C25H23N5O4
|
1
|
| 1 |
IC50 = 830 nM
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|
|
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CP0212639
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1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-methyl-N-phenyl-2-piperidineacetamide
Show/Hide
|
C22H26N6O
|
1
|
| 1 |
IC50 = 885 nM
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|
|
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CP0156642
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1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[(diphenyl)methyl]-2-piperidineacetamide
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|
C27H28N6O
|
1
|
| 1 |
IC50 = 1805 nM
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|
|
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CP0212640
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(2S)-1-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)-N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C22H24N6O3
|
1
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| 1 |
IC50 = 6400 nM
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|
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CP0215282
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2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]-N-[(4-sulfamoylphenyl)methyl]acetamide
Show/Hide
|
C21H25N7O3S
|
1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0486194
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4-(4-(1H-imidazol-1-yl)phenoxy)-2-(benzo[d][1,3]dioxol-5-ylmethyl)-6-chloropyrimidine
Show/Hide
|
C21H15ClN4O3
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0493060
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4-(4-(1H-imidazol-1-yl)phenoxy)-6-(benzo[d][1,3]dioxol-5-yloxy)pyrimidine
Show/Hide
|
C20H14N4O4
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0156641
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N-(1,3-benzodioxol-5-yl)-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C21H22N6O3
|
1
|
| 1 |
IC50 > 100 nM
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|
|
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CP0161025
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1-[2-(1H-imidazol-1-yl)-4-pyrimidinyl]-N-[[4-(methylsulfonylamino)phenyl]methyl]-2-piperidineacetamide
Show/Hide
|
C22H27N7O3S
|
1
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| 1 |
IC50 > 100 nM
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|
|
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CP0193061
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1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-N-methyl-2-piperidineacetamide
Show/Hide
|
C15H20N6O
|
1
|
| 1 |
IC50 > 100 nM
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|
|
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CP0363428
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1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-N-[(3,4,5-trimethoxyphenyl)methyl]-2-piperidineacetamide
Show/Hide
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C24H30N6O4
|
1
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| 1 |
IC50 > 100 nM
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|
|
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CP0538096
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N-[(4-cyanophenyl)methyl]-2-[1-(2-imidazol-1-ylpyrimidin-4-yl)piperidin-2-yl]acetamide
Show/Hide
|
C22H23N7O
|
1
|
| 1 |
IC50 > 100 nM
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