| Compound ID |
Compound Name |
Compound Formula |
|
CP0547973
|
US8754075, 50
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|
C21H21F2N5O3
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0380937
|
US8754075, 38
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|
C19H17F2N5O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0407179
|
US8754075, 1
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|
C17H15ClF2N4O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0544127
|
US8754075, 2
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|
C17H14Cl2F2N4O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0321772
|
N-[3-[(4R,5R)-2-amino-5-fluoro-4-methyl-5,6-dihydro-1,3-oxazin-4-yl]-4-fluorophenyl]-5-cyanopyridine-2-carboxamide
Show/Hide
|
C18H15F2N5O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0397102
|
US8754075, 5
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|
C18H17F3N4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0402998
|
US8754075, 47
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|
C20H17F4N5O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0407680
|
US8754075, 3
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|
C17H14F4N4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0440509
|
US8754075, 45
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|
C19H17ClF4N4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0389314
|
US8754075, 8
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|
C17H14ClF3N4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0414023
|
US8754075, 40
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|
C17H16ClF4N5O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0415557
|
US8754075, 7
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|
C18H14ClF2N5O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0425312
|
US8754075, 39
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|
C18H16Cl2F2N4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0524281
|
US8754075, 6
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|
C18H16F4N4O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0536504
|
US8754075, 46
Show/Hide
|
C19H17F5N4O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0544635
|
US8754075, 9
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|
C18H14ClF5N4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0470138
|
US8754075, 11
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|
C18H16F4N4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0488985
|
US8754075, 48
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|
C19H16Cl2F4N4O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0544631
|
US8754075, 41
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|
C18H17ClF2N4O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0385717
|
US8754075, 14
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|
C22H20F2N4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0403427
|
US8754075, 12
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|
C18H14F6N4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0468441
|
US8754075, 13
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|
C18H18F2N4O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0414721
|
US8754075, 15
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|
C17H15F4N5O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0544844
|
US8754075, 16
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|
C20H21F2N5O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0403473
|
US8754075, 18
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|
C18H19F2N3O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0538398
|
US8754075, 17
Show/Hide
|
C19H17F5N4O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0560289
|
US8754075, 19
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|
C18H17F4N5O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0508727
|
US8754075, 20
Show/Hide
|
C17H15F3N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0374620
|
US8754075, 42
Show/Hide
|
C18H17F3N4O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0538918
|
US8754075, 21
Show/Hide
|
C19H18F4N4O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0401342
|
US8754075, 22
Show/Hide
|
C20H20F2N4O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0559241
|
US8754075, 23
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|
C21H22F2N4O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0546586
|
US8754075, 24
Show/Hide
|
C20H18F6N4O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0470122
|
US8754075, 49
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|
C21H19F7N4O4
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0389338
|
US8754075, 37
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|
C20H19F5N4O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0390398
|
US8754075, 10
Show/Hide
|
C17H16F3N5O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0491020
|
US8754075, 51
Show/Hide
|
C18H14F3N5O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0141731
|
N-[3-[(4R,5S)-2-amino-5-fluoro-4-methyl-5,6-dihydro-1,3-oxazin-4-yl]-4-fluorophenyl]-5-cyanopyridine-2-carboxamide
Show/Hide
|
C18H15F2N5O2
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0538190
|
US8754075, 44
Show/Hide
|
C16H17F4N3O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0487264
|
US8754075, 52
Show/Hide
|
C18H14F3N5O2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0539624
|
US8754075, 34
Show/Hide
|
C17H15ClF2N4O2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0472308
|
US8754075, 25
Show/Hide
|
C20H17F7N4O3
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0470048
|
US8754075, 31
Show/Hide
|
C16H16F2N4O2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0385263
|
US8754075, 26
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|
C15H13ClF2N4O2S
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0512536
|
US8754075, 35
Show/Hide
|
C18H14ClF2N5O2
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0389388
|
US8754075, 27
Show/Hide
|
C17H16F5N5O2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0472513
|
US8754075, 28
Show/Hide
|
C15H14ClF2N5O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0422514
|
US8754075, 36
Show/Hide
|
C18H14ClF5N4O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0396417
|
US8754075, 43
Show/Hide
|
C18H18ClF4N5O2
|
1
|
| 1 |
IC50 = 183 nM
|
|
|
|
CP0375690
|
US8754075, 29
Show/Hide
|
C15H14F2N4O2S
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0413975
|
US8754075, 32
Show/Hide
|
C15H17F2N3O2
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0462716
|
US8754075, 30
Show/Hide
|
C17H19F2N5O2
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
