Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8754075, 49
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 PubChem ID
CID: 66559100
SID: 152189555
Canonical SMILES
C[C@@]1(N=C(N)OC[C@@H]1OCC(F)(F)F)c1cc(NC(=O)c2ccc(OCC(F)(F)F)cn2)ccc1F
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Compound Formula C21H19F7N4O4
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000416 INS-1E
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS