Brief Information of the Cell Line and Protein
Cell Line ID: CL000410 , SJSA-1
 Cell Line Info 
Synonyms
SJSA1
SJSA
OsA-CL
OSA-CL
OsACL
OSACL
Os-A
OSA
OsA
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1697
Protein ID: PT01771 , E3 ubiquitin-protein ligase Mdm2
 Protein Info 
Gene Name MDM2
Organism Homo sapiens, Human
Protein Classification Other nuclear protein
Uniprot ID Q00987
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000410
 Cell Line Info 
 Protein ID: PT01771
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0141684
 Compound Info 
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(cyclopropylmethyl)-2-oxopiperidin-3-yl]acetic acid
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C23H23Cl2NO3
  2
1
IC50 = 3400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 18100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385247
 Compound Info 
(2R)-2-[(2S,3R,6S)-2,3-bis(4-chlorophenyl)-6-[(4-fluorophenyl)methyl]-5-oxomorpholin-4-yl]pentanoic acid
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C28H26Cl2FNO4
  2
1
IC50 = 5900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 20700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0448902
 Compound Info 
2-[(3S,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(cyclopropylmethyl)-2-oxopiperidin-3-yl]acetic acid
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C23H23Cl2NO3
  2
1
IC50 = 7100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 25200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0490906
 Compound Info 
2-[(2S,5R,6R)-6-(3-chlorophenyl)-5-(4-chlorophenyl)-4-(cyclopropylmethyl)-3-oxomorpholin-2-yl]acetic acid
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C22H21Cl2NO4
  1
1
IC50 = 15300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0528670
 Compound Info 
2-[(2R,5R,6R)-6-(3-chlorophenyl)-5-(4-chlorophenyl)-4-(cyclopropylmethyl)-3-oxomorpholin-2-yl]acetic acid
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C22H21Cl2NO4
  1
1
IC50 = 16700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0328587
 Compound Info 
2-[(2S,5R,6S)-6-(3-chlorophenyl)-5-(4-chlorophenyl)-4-(cyclopropylmethyl)-3-oxomorpholin-2-yl]acetic acid
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C22H21Cl2NO4
  1
1
IC50 = 29400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS