Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(cyclopropylmethyl)-2-oxopiperidin-3-yl]acetic acid
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 PubChem ID
CID: 56591370
SID: 134218624
Canonical SMILES
OC(=O)C[C@H]1C[C@@H]([C@H](N(CC2CC2)C1=O)c1ccc(Cl)cc1)c1cccc(Cl)c1
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Compound Formula C23H23Cl2NO3
Compound Structure
Protein Name
 Protein Info 
E3 ubiquitin-protein ligase Mdm2
Protein Classification
Other nuclear protein
Uniprot ID
Q00987
Gene Name
MDM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000410 SJSA-1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
2
IC50 = 18100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 34 nM