Brief Information of the Cell Line and Protein
Cell Line ID: CL000330 , CHO Pro-4 MtxRII OuaR-2-4
 Cell Line Info 
Synonyms
Pro-4 MtxRII OuaR 2-4
MTXRIIOuaR2-4
R2
Category Transformed cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_C5SG
Protein ID: PT04881 , Folate receptor alpha
 Protein Info 
Gene Name FOLR1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P15328
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000330
 Cell Line Info 
 Protein ID: PT04881
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0915863
 Compound Info 
(5-(3-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)propyl)thiophene-2-carbonyl)-L-glutamic acid
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C19H20N4O6S2
  1
1
IC50 = 0.34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0958003
 Compound Info 
(4-(3-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)propyl)thiophene-2-carbonyl)-L-glutamic acid
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C19H20N4O6S2
  1
1
IC50 = 0.44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0882698
 Compound Info 
(5-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl)thiophene-3-carbonyl)-L-glutamic acid
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C20H22N4O6S2
  1
1
IC50 = 0.91 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0915865
 Compound Info 
(5-(3-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)propyl)thiophene-3-carbonyl)-L-glutamic acid
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C19H20N4O6S2
  1
1
IC50 = 1.08 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0915862
 Compound Info 
(5-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl)thiophene-2-carbonyl)-L-glutamic acid
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C20H22N4O6S2
  1
1
IC50 = 2.55 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0915864
 Compound Info 
(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl)thiophene-2-carbonyl)-L-glutamic acid
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C20H22N4O6S2
  1
1
IC50 = 5.62 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0035062
 Compound Info 
(S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl)benzamido)pentanedioic acid
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C22H24N4O6S
  1
1
IC50 = 9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0915866
 Compound Info 
(5-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)butyl)furan-2-carbonyl)-L-glutamic acid
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C20H22N4O7S
  1
1
IC50 = 10.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS