| Compound ID |
Compound Name |
Compound Formula |
|
CP0569742
|
2-[[2-(benzylsulfonylamino)-6-oxo-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C14H14N4O6S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0550578
|
2-[[6-oxo-2-[(4-phenylphenyl)sulfonylamino]-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C19H16N4O6S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0550577
|
2-[[2-[(4-methoxyphenyl)sulfonylamino]-6-oxo-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C14H14N4O7S
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0579565
|
2-[[2-[(3-chlorophenyl)sulfonylamino]-6-oxo-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C13H11ClN4O6S
|
1
|
| 1 |
EC50 = 1250 nM
|
|
|
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CP0579651
|
2-[[2-[(3,4-dichlorophenyl)sulfonylamino]-6-oxo-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C13H10Cl2N4O6S
|
1
|
| 1 |
EC50 = 4460 nM
|
|
|
|
CP0579961
|
2-[[6-oxo-2-[[4-(trifluoromethyl)phenyl]sulfonylamino]-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C14H11F3N4O6S
|
1
|
| 1 |
EC50 = 4910 nM
|
|
|
|
CP0577132
|
2-[[2-[(4-chlorophenyl)sulfonylamino]-6-oxo-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C13H11ClN4O6S
|
1
|
| 1 |
EC50 = 5540 nM
|
|
|
|
CP0068717
|
2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
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|
C19H16N2O5
|
1
|
| 1 |
EC50 = 6110 nM
|
|
|
|
CP0579962
|
2-[[2-[(4-bromophenyl)sulfonylamino]-6-oxo-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C13H11BrN4O6S
|
1
|
| 1 |
EC50 = 7970 nM
|
|
|
|
CP0580036
|
2-[[2-[(4-methylphenyl)sulfonylamino]-6-oxo-1H-pyrimidine-5-carbonyl]amino]acetic acid
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|
C14H14N4O6S
|
1
|
| 1 |
EC50 = 9270 nM
|
|
|
|
CP0556300
|
2-[2-(5-cyano-3-hydroxy-4-methylpyridin-2-yl)-5-methyl-1,3-thiazol-4-yl]-N-[2-(diethylamino)ethyl]acetamide
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|
C19H25N5O2S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0379966
|
2-[2-(5-cyano-3-hydroxy-4-methylpyridin-2-yl)-1,3-thiazol-4-yl]-N-(2-pyridin-2-ylethyl)acetamide
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|
C19H17N5O2S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0375411
|
2-[2-(5-cyano-3-hydroxy-4-methylpyridin-2-yl)-5-methyl-1,3-thiazol-4-yl]-N-(2-pyridin-2-ylethyl)acetamide
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|
C20H19N5O2S
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0379245
|
2-[2-(5-cyano-3-hydroxypyridin-2-yl)-5-methyl-1,3-thiazol-4-yl]-N-(2-pyridin-2-ylethyl)acetamide
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|
C19H17N5O2S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0386850
|
2-[2-(5-cyano-3-hydroxy-4-methylpyridin-2-yl)-5-methyl-1,3-thiazol-4-yl]-N-ethylacetamide
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|
C15H16N4O2S
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0556319
|
5-hydroxy-6-[4-(2-oxo-2-pyrrolidin-1-ylethyl)-1,3-thiazol-2-yl]pyridine-3-carbonitrile
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|
C15H14N4O2S
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0508040
|
2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]-N-[(1R)-2-hydroxy-1-phenylethyl]acetamide
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|
C19H16N4O3S
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0480509
|
2-[[2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl]amino]acetic acid
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|
C13H10N4O4S
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0386872
|
2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]-N-[(1S)-2-hydroxy-1-phenylethyl]acetamide
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|
C19H16N4O3S
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0433524
|
(2R)-2-[[2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl]amino]-2-phenylacetic acid
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|
C19H14N4O4S
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0574610
|
(2S)-2-[[2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl]amino]-2-phenylacetic acid
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|
C19H14N4O4S
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0389133
|
2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]-N-(2-pyridin-2-ylethyl)acetamide
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|
C18H15N5O2S
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0386849
|
2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]-N-(2-phenylethyl)acetamide
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|
C19H16N4O2S
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0556318
|
2-[2-(5-cyano-3-hydroxy-4-methylpyridin-2-yl)-1,3-thiazol-4-yl]-N-[2-(diethylamino)ethyl]acetamide
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|
C18H23N5O2S
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0114319
|
2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)acetic acid
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|
C12H9ClN2O4
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0386851
|
N-benzyl-2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetamide
Show/Hide
|
C18H14N4O2S
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0433523
|
2-[2-(5-cyano-3-hydroxy-4-methylpyridin-2-yl)-5-phenyl-1,3-thiazol-4-yl]-N-(2-pyridin-2-ylethyl)acetamide
Show/Hide
|
C25H21N5O2S
|
1
|
| 1 |
IC50 = 5700 nM
|
|
|
|
CP0558707
|
2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetic acid
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|
C11H7N3O3S
|
1
|
| 1 |
IC50 = 6000 nM
|
|
|
|
CP0556299
|
2-[[2-[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl]amino]-2-methylpropanoic acid
Show/Hide
|
C15H14N4O4S
|
1
|
| 1 |
IC50 = 7300 nM
|
|
|
|
CP0543216
|
2-[2-(5-cyano-3-hydroxypyridin-2-yl)-6-oxo-1H-pyrimidin-5-yl]acetic acid
Show/Hide
|
C12H8N4O4
|
1
|
| 1 |
IC50 = 13500 nM
|
|
|
|
CP0459782
|
2-[2-(5-cyano-3-hydroxypyridin-2-yl)-5-phenyl-1,3-thiazol-4-yl]-N-(2-pyridin-2-ylethyl)acetamide
Show/Hide
|
C24H19N5O2S
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0459735
|
2-[2-(3-hydroxypyridin-2-yl)-6-oxo-1H-pyrimidin-5-yl]acetic acid
Show/Hide
|
C11H9N3O4
|
1
|
| 1 |
IC50 = 27500 nM
|
|
|
|
CP0558708
|
N-benzyl-2-[2-(3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetamide
Show/Hide
|
C17H15N3O2S
|
1
|
| 1 |
IC50 = 81000 nM
|
|
|
