Brief Information of the Cell Line and Protein
Cell Line ID: CL000207 , MIA PaCa-2
 Cell Line Info 
Synonyms
MIA-PaCa-2
MIA-PACA-2
MIA-Pa-Ca-2
MIA Paca2
MIA PaCa2
MiaPaCa-2
MIAPACA-2
MiaPaca.2
MiaPaCa2
Miapaca2
MIAPaCa2
MIAPACA2
Mia PACA 2
MIAPaCa-2
PaCa2
MiaPaCa
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0428
Protein ID: PT01252 , Serine/threonine-protein kinase PLK1
 Protein Info 
Gene Name PLK1
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P53350
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000207
 Cell Line Info 
 Protein ID: PT01252
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0054396
 Compound Info 
3-(tert-butylamino)-4-[[2-(4-pyridin-4-ylanilino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C23H22N6O2
  1
1
EC50 = 1050 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0071268
 Compound Info 
3-[[2-[(1-acetyl-2,3-dihydroindol-5-yl)amino]pyrimidin-4-yl]amino]-4-(tert-butylamino)cyclobut-3-ene-1,2-dione
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C22H24N6O3
  1
1
EC50 = 1470 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077493
 Compound Info 
3-(tert-butylamino)-4-[[2-(1H-indazol-5-ylamino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C19H19N7O2
  1
1
EC50 = 1470 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388384
 Compound Info 
3-(tert-butylamino)-4-[[2-[4-(1H-pyrazol-4-yl)anilino]pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C21H21N7O2
  1
1
EC50 = 1610 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0282697
 Compound Info 
3-(tert-butylamino)-4-[[2-(4-pyridin-3-ylanilino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C23H22N6O2
  1
1
EC50 = 2550 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0335238
 Compound Info 
3-[[2-(1,3-benzothiazol-6-ylamino)pyrimidin-4-yl]amino]-4-(tert-butylamino)cyclobut-3-ene-1,2-dione
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C19H18N6O2S
  1
1
EC50 = 2860 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0566811
 Compound Info 
3-(tert-butylamino)-4-[[2-(2,3-dihydro-1-benzofuran-5-ylamino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C20H21N5O3
  1
1
EC50 = 2860 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0391978
 Compound Info 
3-(tert-butylamino)-4-[[2-(9H-carbazol-2-ylamino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C24H22N6O2
  1
1
EC50 = 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0430291
 Compound Info 
3-(tert-butylamino)-4-[[2-(4-pyridin-2-ylanilino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C23H22N6O2
  1
1
EC50 = 8280 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0282699
 Compound Info 
3-(tert-butylamino)-4-[[2-[4-(thiadiazol-4-yl)anilino]pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C20H19N7O2S
  1
1
EC50 = 8320 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0331679
 Compound Info 
3-(tert-butylamino)-4-[[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C22H26N6O3
  1
1
EC50 = 8890 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0217497
 Compound Info 
3-(tert-butylamino)-4-[[2-(9H-fluoren-2-ylamino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C25H23N5O2
  1
1
EC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0274254
 Compound Info 
3-(tert-butylamino)-4-[[2-(4-phenylanilino)pyrimidin-4-yl]amino]cyclobut-3-ene-1,2-dione
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C24H23N5O2
  1
1
EC50 > 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS