Brief Information of the Compound and Protein
Compound Name
3-[[2-[(1-acetyl-2,3-dihydroindol-5-yl)amino]pyrimidin-4-yl]amino]-4-(tert-butylamino)cyclobut-3-ene-1,2-dione
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PubChem ID
CID: 71463025
SID: 163526679
Canonical SMILES
CC(=O)N1CCc2cc(Nc3nccc(Nc4c(NC(C)(C)C)c(=O)c4=O)n3)ccc12
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Compound Formula C22H24N6O3
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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Other protein kinase group
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Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000207 MIA PaCa-2 Homo sapiens (Human)  1
1
EC50 = 1470 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 20 nM