Brief Information of the Cell Line and Protein
Cell Line ID: CL000194 , RBL-1
Synonyms
RBL 1
RBL-I
RBL
Rat Basophilic Leukemia-1
Category Cancer cell line
Organism
Rattus norvegicus (Rat)
Cellosaurus ID
CVCL_0496
Protein ID: PT06758 , Hematopoietic prostaglandin D synthase
Gene Name HPGDS
Organism Rattus norvegicus, Rat
Protein Classification Enzyme
Uniprot ID O35543
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000194  Protein ID: PT06758
 
Compound ID Compound Name Compound Formula
CP0559114
2-phenyl-N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]imidazo[1,2-a]pyridine-6-carboxamide
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C21H21F3N4O
 1
1
IC50 = 84 nM
   TI
   LI
   LO
   TS
CP0559650
N-[4-(2-hydroxypropan-2-yl)cyclohexyl]-2-phenylimidazo[1,2-a]pyridine-6-carboxamide
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C23H27N3O2
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0176712
2-(2-fluorophenyl)-N-[4-(2-hydroxypropan-2-yl)cyclohexyl]imidazo[1,2-a]pyridine-6-carboxamide
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C23H26FN3O2
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0576192
2-(3-fluorophenyl)-N-[4-(2-hydroxypropan-2-yl)cyclohexyl]imidazo[1,2-a]pyridine-6-carboxamide
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C23H26FN3O2
 1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
CP0559612
2-(2-fluorophenyl)-N-[(3R,6S)-6-(2-hydroxypropan-2-yl)oxan-3-yl]imidazo[1,2-a]pyridine-6-carboxamide
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C22H24FN3O3
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0444546
1-(3-fluorophenyl)-N-[4-(2-hydroxypropan-2-yl)cyclohexyl]indazole-5-carboxamide
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C23H26FN3O2
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0176713
N-[(3R,6S)-6-(2-hydroxypropan-2-yl)oxan-3-yl]-2-phenylimidazo[1,2-a]pyridine-6-carboxamide
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C22H25N3O3
 1
1
IC50 = 460 nM
   TI
   LI
   LO
   TS
CP0354550
1-(3-fluorophenyl)-N-[4-(2-hydroxypropan-2-yl)cyclohexyl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide
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C22H29FN4O2
 1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS
CP0176714
2-(3-fluorophenyl)-N-[(3R,6S)-6-(2-hydroxypropan-2-yl)oxan-3-yl]imidazo[1,2-a]pyridine-6-carboxamide
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C22H24FN3O3
 1
1
IC50 = 710 nM
   TI
   LI
   LO
   TS
CP0176715
1-(3-fluorophenyl)-N-[4-(2-hydroxypropan-2-yl)cyclohexyl]indole-5-carboxamide
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C24H27FN2O2
 1
1
IC50 = 780 nM
   TI
   LI
   LO
   TS
CP0562079
2-(4-fluorophenyl)-N-[4-(2-hydroxypropan-2-yl)cyclohexyl]imidazo[1,2-a]pyridine-6-carboxamide
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C23H26FN3O2
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0444545
N-(1-ethylpiperidin-4-yl)-2-phenylimidazo[1,2-a]pyridine-6-carboxamide
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C21H24N4O
 1
1
IC50 = 4300 nM
   TI
   LI
   LO
   TS