| Compound ID |
Compound Name |
Compound Formula |
|
CP0079810
|
2-(Dimethylamino)ethyl p-(butylamino)benzoate
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|
C15H24N2O2
|
2
|
| 1 |
IC50 = 56 nM
|
|
|
| 2 |
IC50 = 320 nM
|
|
|
|
CP0383167
|
2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxy-1-morpholin-4-ylpropan-1-one
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|
C20H19F2N3O3
|
2
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 620 nM
|
|
|
|
CP0380327
|
4-[1-(2-fluorophenyl)indazol-4-yl]-1-[2-[(3S)-3-fluoropyrrolidin-1-yl]-2-oxoethyl]piperazin-2-one
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|
C23H23F2N5O2
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 540 nM
|
|
|
|
CP0409746
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[(6-methylpyrazin-2-yl)methyl]imidazolidin-2-one
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|
C22H19FN6O
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0455925
|
1-[2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxyethyl]-3-methylimidazolidin-2-one
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|
C19H18F2N4O2
|
2
|
| 1 |
IC50 = 320 nM
|
|
|
| 2 |
IC50 = 1200 nM
|
|
|
|
CP0390679
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(pyridin-4-yl)imidazolidin-2-one
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|
C21H16FN5O
|
2
|
| 1 |
IC50 = 330 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
|
CP0409748
|
(3aR,6aS)-5-[1-(2-fluorophenyl)indazol-4-yl]-2-(3-hydroxy-3-methylbutanoyl)-3,3a,6,6a-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-4-one
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|
C24H25FN4O3
|
2
|
| 1 |
IC50 = 340 nM
|
|
|
| 2 |
IC50 = 3900 nM
|
|
|
|
CP0399321
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(3S)-3-fluoropyrrolidin-1-yl]-2-oxoethyl}imidazolidin-2-one
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|
C22H21F2N5O2
|
3
|
| 1 |
IC50 = 370 nM
|
|
|
| 2 |
IC50 = 480 nM
|
|
|
| 3 |
IC50 = 570 nM
|
|
|
|
CP0420263
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(4-methyl-2-oxopentyl)imidazolidin-2-one
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|
C22H23FN4O2
|
2
|
| 1 |
IC50 = 570 nM
|
|
|
| 2 |
IC50 = 5100 nM
|
|
|
|
CP0390700
|
tert-butyl N-[2-[1-(2-fluorophenyl)indazol-4-yl]oxyethyl]carbamate
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|
C20H22FN3O3
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0401782
|
2-benzyl-5-[1-(2-fluorophenyl)indazol-4-yl]-3,3a,6,6a-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-4-one
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|
C26H23FN4O
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0486876
|
US9783527, Example 2
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|
C21H21FN4O3
|
2
|
| 1 |
IC50 = 730 nM
|
|
|
| 2 |
IC50 = 2300 nM
|
|
|
|
CP0398799
|
2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxy-1-morpholin-4-ylethanone
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|
C19H17F2N3O3
|
2
|
| 1 |
IC50 = 760 nM
|
|
|
| 2 |
IC50 = 1400 nM
|
|
|
|
CP0380326
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl]imidazolidin-2-one
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|
C22H22FN5O2
|
2
|
| 1 |
IC50 = 810 nM
|
|
|
| 2 |
IC50 = 990 nM
|
|
|
|
CP0409811
|
2-{3-[1-(2-fluorophenyl)-1H-indazol-4-yl]-2-oxoimidazolidin-1-yl}acetamide
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|
C18H16FN5O2
|
2
|
| 1 |
IC50 = 840 nM
|
|
|
| 2 |
IC50 = 2500 nM
|
|
|
|
CP0409745
|
1-[1-(2-fluorophenyl)-1H-
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|
C22H21F2N5O2
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0409812
|
N-cyclopropyl-2-{3-[1-(2-fluorophenyl)-1H-indazol-4-yl]-2-oxoimidazolidin-1-yl}acetamide
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|
C21H20FN5O2
|
2
|
| 1 |
IC50 = 920 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0409170
|
3-[2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxyethyl]-1H-imidazol-2-one
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|
C18H14F2N4O2
|
1
|
| 1 |
IC50 = 960 nM
|
|
|
|
CP0399326
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(3S)-3-fluoropiperidin-1-yl]-2-oxoethyl}imidazolidin-2-one
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|
C23H23F2N5O2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0409171
|
5-fluoro-1-(2-fluorophenyl)-3-(2-imidazol-1-ylethoxy)indazole
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|
C18H14F2N4O
|
2
|
| 1 |
IC50 = 1100 nM
|
|
|
| 2 |
IC50 = 7000 nM
|
|
|
|
CP0490523
|
(3aS,6aS)-5-[1-(2-fluorophenyl)indazol-4-yl]-1-(3-hydroxy-3-methylbutanoyl)-3,3a,4,6a-tetrahydro-2H-pyrrolo[2,3-c]pyrrol-6-one
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|
C24H25FN4O3
|
1
|
| 1 |
IC50 = 1350 nM
|
|
|
|
CP0490518
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-oxazol-2-ylmethyl)imidazolidin-2-one
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|
C20H16FN5O2
|
2
|
| 1 |
IC50 = 1500 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0383166
|
1-[2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxyethyl]imidazolidin-2-one
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|
C18H16F2N4O2
|
2
|
| 1 |
IC50 = 1900 nM
|
|
|
| 2 |
IC50 = 2700 nM
|
|
|
|
CP0390699
|
1-[2-[1-(2,4-difluorophenyl)-5-fluoroindazol-3-yl]oxyethyl]imidazolidin-2-one
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|
C18H15F3N4O2
|
2
|
| 1 |
IC50 = 2000 nM
|
|
|
| 2 |
IC50 = 12000 nM
|
|
|
|
CP0447860
|
3-[2-[5-fluoro-1-(2-fluorophenyl)indazol-3-yl]oxyethyl]-1,3-oxazolidin-2-one
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|
C18H15F2N3O3
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0420262
|
1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(3S)-3-hydroxypyrrolidin-1-yl]-2-oxoethyl}imidazolidin-2-one
Show/Hide
|
C22H22FN5O3
|
2
|
| 1 |
IC50 = 2720 nM
|
|
|
| 2 |
IC50 = 9000 nM
|
|
|
|
CP0409808
|
1-[2-[5-fluoro-1-(4-fluorophenyl)indazol-3-yl]oxyethyl]imidazolidin-2-one
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|
C18H16F2N4O2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
