Brief Information of the Cell Line and Protein
Cell Line ID: CL000131 , HEK293-F
 Cell Line Info 
Synonyms
HEK-293-F
HEK 293-F
HEK-293F
HEK293F
293-F
293 F
293F
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_6642
Protein ID: PT00995 , Histone deacetylase 3
 Protein Info 
Gene Name HDAC3
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID O15379
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000131
 Cell Line Info 
 Protein ID: PT00995
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0138710
 Compound Info 
(2S)-6-(cyclopropylmethyl)-N-[(1S)-1-[5-(7-methoxy-2-methylquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C35H46N4O4
  1
1
IC50 = 0.08 nM
 Bioactivity Info 
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CP0636220
 Compound Info 
(S)-N-(1-(5-(2-fluorophenyl)-1H-imidazol-2-yl)-7-(isoxazol-3-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide
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C24H28FN5O3
  1
1
IC50 = 0.087 nM
 Bioactivity Info 
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CP0955941
 Compound Info 
(S)-6-(cyclopropylmethyl)-N-((S)-1-(5-(7-methoxyquinolin-6-yl)-1H-imidazol-2-yl)-7-oxononyl)-6-azaspiro[2.5]octane-1-carboxamide
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C34H45N5O3
  1
1
IC50 = 0.1 nM
 Bioactivity Info 
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CP0678023
 Compound Info 
(S)-6-ethyl-N-((S)-1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)-7-oxononyl)-6-azaspiro[2.5]octane-1-carboxamide
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C32H43N5O3
  1
1
IC50 = 0.24 nM
 Bioactivity Info 
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CP0543661
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(7-methoxy-2-methylquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C33H44N4O4
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0568215
 Compound Info 
(2S)-6-(cyclopropylmethyl)-N-[(1S)-1-[5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C35H47N5O3
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0568333
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-fluoro-2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C31H40FN5O2
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0570249
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-propan-2-yl-6-azaspiro[2.5]octane-2-carboxamide
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C34H47N5O3
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0570394
 Compound Info 
(2S)-N-[(1S)-1-[5-(2-cyclopropylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C33H43N5O2
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0571293
 Compound Info 
(2S)-6-cyclobutyl-N-[(1S)-1-[5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C35H47N5O3
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0577129
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(7-methoxy-1-methyl-2-oxoquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C33H45N5O4
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0577441
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C33H45N5O3
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0577442
 Compound Info 
(2S)-N-[(1S)-1-[5-(2,7-dimethylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C32H43N5O2
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0577445
 Compound Info 
(2S)-6-(cyclopropylmethyl)-N-[(1S)-1-[5-(2-ethyl-7-methoxyquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C36H49N5O3
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0577692
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-methoxy-2-methylquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C32H42N4O4
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0577693
 Compound Info 
(2S)-N-[(1S)-1-[5-(2-cyclopropyl-7-methoxyquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C34H45N5O3
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0579552
 Compound Info 
(2S)-N-[(1S)-1-[5-(2-cyclopropyl-7-methoxyquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-(cyclopropylmethyl)-6-azaspiro[2.5]octane-2-carboxamide
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C37H49N5O3
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0832315
 Compound Info 
(S)-6-methyl-N-((S)-1-(5-(2-methyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-1H-imidazol-2-yl)-7-oxononyl)-6-azaspiro[2.5]octane-1-carboxamide
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C31H41N5O3
  1
1
IC50 < 0.3 nM
 Bioactivity Info 
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CP0577440
 Compound Info 
(2S)-6-methyl-N-[(1S)-1-[5-(2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O2
  1
1
IC50 = 0.33 nM
 Bioactivity Info 
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CP0543657
 Compound Info 
(2S)-N-[(1S)-1-[5-(2-ethylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C32H43N5O2
  1
1
IC50 = 0.34 nM
 Bioactivity Info 
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CP0569796
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-methoxyquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O3
  1
1
IC50 = 0.36 nM
 Bioactivity Info 
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CP0579646
 Compound Info 
(2S)-N-[(1S)-1-[5-(2-methoxy-1,7-naphthyridin-3-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C30H40N6O3
  1
1
IC50 = 0.37 nM
 Bioactivity Info 
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CP0543659
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-[5-(2-pyrrolidin-1-ylquinolin-6-yl)-1H-imidazol-2-yl]nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C34H46N6O2
  1
1
IC50 = 0.4 nM
 Bioactivity Info 
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CP0578926
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(7-methoxy-1-methyl-2-oxoquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C33H44N4O5
  1
1
IC50 = 0.4 nM
 Bioactivity Info 
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CP0568214
 Compound Info 
(2S)-N-[(1S)-1-[5-(2-methoxyquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O3
  1
1
IC50 = 0.41 nM
 Bioactivity Info 
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CP0965642
 Compound Info 
(S)-N-((S)-1-(5-(7-methoxy-2-(pyrrolidin-1-yl)quinolin-6-yl)-1H-imidazol-2-yl)-7-oxononyl)-6-methyl-6-azaspiro[2.5]octane-1-carboxamide
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C35H48N6O3
  1
1
IC50 = 0.42 nM
 Bioactivity Info 
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CP0578925
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-[5-(4-pyridin-3-ylphenyl)-1H-imidazol-2-yl]nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C32H41N5O2
  1
1
IC50 = 0.45 nM
 Bioactivity Info 
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CP0569795
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-[5-(4-pyridin-4-ylphenyl)-1H-imidazol-2-yl]nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C32H41N5O2
  1
1
IC50 = 0.46 nM
 Bioactivity Info 
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CP0569430
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(2-methoxy-1,7-naphthyridin-3-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O4
  1
1
IC50 = 0.49 nM
 Bioactivity Info 
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CP0577128
 Compound Info 
(2S)-6-methyl-N-[(1S)-1-[5-[2-(1,3-oxazol-2-yl)quinolin-6-yl]-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C33H40N6O3
  1
1
IC50 = 0.51 nM
 Bioactivity Info 
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CP0568320
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-ethyl-2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C33H45N5O2
  1
1
IC50 = 0.54 nM
 Bioactivity Info 
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CP0568325
 Compound Info 
(2S)-6-methyl-N-[(1S)-1-[5-(2-methylindazol-5-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C29H40N6O2
  1
1
IC50 = 0.54 nM
 Bioactivity Info 
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CP0637739
 Compound Info 
(S)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)-7-oxononyl)-1-methylazetidine-3-carboxamide
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C27H35N5O3
  1
1
IC50 = 0.6 nM
 Bioactivity Info 
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CP0569431
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-(5-quinolin-6-yl-1H-imidazol-2-yl)nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C30H39N5O2
  1
1
IC50 = 0.63 nM
 Bioactivity Info 
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CP0545443
 Compound Info 
(2S)-6-ethyl-N-[(1S)-7-oxo-1-[5-(2-oxo-6-phenyl-1H-pyridin-3-yl)-1H-imidazol-2-yl]nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C33H43N5O3
  1
1
IC50 = 0.67 nM
 Bioactivity Info 
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CP0579557
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-[5-(4-pyrazin-2-ylphenyl)-1H-imidazol-2-yl]nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H40N6O2
  1
1
IC50 = 0.75 nM
 Bioactivity Info 
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CP0568319
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-[5-(2-pyrazol-1-ylquinolin-6-yl)-1H-imidazol-2-yl]nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C33H41N7O2
  1
1
IC50 = 1 nM
 Bioactivity Info 
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CP0826898
 Compound Info 
(S)-6-methyl-N-((S)-7-oxo-1-(5-(quinolin-3-yl)-1H-imidazol-2-yl)nonyl)-6-azaspiro[2.5]octane-1-carboxamide
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C30H39N5O2
  1
1
IC50 = 1.1 nM
 Bioactivity Info 
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CP0545445
 Compound Info 
(2S)-6-methyl-N-[(1S)-1-[5-(1-methyl-2-oxoquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O3
  1
1
IC50 = 1.2 nM
 Bioactivity Info 
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CP0570395
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-fluoro-2-methylquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C31H39FN4O3
  1
1
IC50 = 1.3 nM
 Bioactivity Info 
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CP0531517
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-methoxyquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C31H40N4O4
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0547778
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(7-methoxyquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C32H42N4O4
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0955940
 Compound Info 
(S)-6-ethyl-N-((S)-1-(5-(7-methoxyquinolin-6-yl)-1H-imidazol-2-yl)-7-oxononyl)-6-azaspiro[2.5]octane-1-carboxamide
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C32H43N5O3
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0543658
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-(5-isoquinolin-6-yl-1H-imidazol-2-yl)-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O2
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0543663
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-[5-(4-pyridin-3-ylphenyl)-1,3-oxazol-2-yl]nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C32H40N4O3
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0568220
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-[5-(2-oxo-1H-quinolin-3-yl)-1H-imidazol-2-yl]nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C30H39N5O3
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0569794
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-chloro-2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C31H40ClN5O2
  1
1
IC50 = 1.5 nM
 Bioactivity Info 
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CP0577438
 Compound Info 
(2S)-6-methyl-N-[(1S)-1-[5-(1-methyl-2-oxoquinolin-3-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O3
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0577443
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(2-ethyl-7-methoxy-1-oxoisoquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C34H46N4O5
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0579394
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(2-methoxy-1,8-naphthyridin-3-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O4
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0579476
 Compound Info 
(2S)-N-[(1S)-1-[5-(7-methoxy-2-methylquinolin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C32H43N5O3
  1
1
IC50 < 1.5 nM
 Bioactivity Info 
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CP0569672
 Compound Info 
(3S,6R,9R,12R)-3-[(2S)-butan-2-yl]-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
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C34H49N5O6
  1
1
IC50 = 1.7 nM
 Bioactivity Info 
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CP0570396
 Compound Info 
(2S)-N-[(1S)-1-[5-(2-cyclopropyl-7-fluoroquinolin-6-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C33H41FN4O3
  1
1
IC50 = 1.9 nM
 Bioactivity Info 
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CP0572973
 Compound Info 
(2S)-N-[(1S)-1-[5-(3a,7a-dihydro-1,3-benzothiazol-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C28H39N5O2S
  1
1
IC50 = 2.2 nM
 Bioactivity Info 
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CP0543662
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(6-methoxy-2-methylindazol-5-yl)-1,3-oxazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H43N5O4
  1
1
IC50 = 2.3 nM
 Bioactivity Info 
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CP0577444
 Compound Info 
(2S)-N-[(1S)-1-[5-(3a,7a-dihydro-1,3-benzoxazol-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C28H39N5O3
  1
1
IC50 = 2.3 nM
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CP0543660
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(7-methoxyquinoxalin-6-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H42N6O3
  1
1
IC50 = 2.6 nM
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CP0580117
 Compound Info 
(2S)-6-methyl-N-[(1S)-1-[5-(1,8-naphthyridin-3-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C29H38N6O2
  1
1
IC50 = 3.8 nM
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CP0545442
 Compound Info 
(2S)-N-[(1S)-1-(5-cinnolin-6-yl-1H-imidazol-2-yl)-7-oxononyl]-6-methyl-6-azaspiro[2.5]octane-2-carboxamide
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C29H38N6O2
  1
1
IC50 = 4.6 nM
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CP0906813
 Compound Info 
3-amino-2-(5-hydroxy-2-methyl-1H-indol-3-yl)-N-((S)-1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)pentyl)propanamide
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C30H34N6O3
  1
1
IC50 = 4.7 nM
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CP0569432
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-[5-(6-methoxy-2-methylindazol-5-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H44N6O3
  1
1
IC50 = 5 nM
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CP0578924
 Compound Info 
(2S)-6-ethyl-N-[(1S)-1-(5-isoquinolin-7-yl-1H-imidazol-2-yl)-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O2
  1
1
IC50 = 5.2 nM
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CP0577439
 Compound Info 
(2S)-6-methyl-N-[(1S)-7-oxo-1-(5-quinoxalin-6-yl-1H-imidazol-2-yl)nonyl]-6-azaspiro[2.5]octane-2-carboxamide
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C29H38N6O2
  1
1
IC50 = 6.2 nM
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CP0038690
 Compound Info 
(2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
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C15H14N2O4S
  1
1
IC50 = 7.3 nM
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CP0749584
 Compound Info 
(S)-N-(5-(2-fluoro-6-hydroxybenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C29H26FN5O3S
  1
1
IC50 = 7.6 nM
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CP0955787
 Compound Info 
(S)-N-(5-(2-amino-6-fluorobenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C29H27FN6O2S
  1
1
IC50 = 9.3 nM
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CP0579915
 Compound Info 
(2S)-6-methyl-N-[(1S)-1-[5-(1-methyl-4-oxoquinolin-3-yl)-1H-imidazol-2-yl]-7-oxononyl]-6-azaspiro[2.5]octane-2-carboxamide
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C31H41N5O3
  1
1
IC50 = 10 nM
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CP0840086
 Compound Info 
(S)-N-(5-(2-hydroxybenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C29H27N5O3S
  1
1
IC50 = 12 nM
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CP0951200
 Compound Info 
3-amino-2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-((S)-1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)pentyl)propanamide
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C31H36N6O3
  1
1
IC50 = 18 nM
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CP0568450
 Compound Info 
(7S)-7-[[2-(5-cyanoindol-1-yl)acetyl]amino]-7-[5-[4-[(dimethylamino)methyl]phenyl]-1,3-oxazol-2-yl]-N-methylheptanamide
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C31H36N6O3
  1
1
IC50 = 26 nM
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CP0742396
 Compound Info 
(S)-N-(5-(2-(methylthio)benzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H29N5O2S2
  1
1
IC50 = 29 nM
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CP0003832
 Compound Info 
N'-hydroxy-N-phenyloctanediamide
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C14H20N2O3
  1
1
IC50 = 29 nM
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CP0831925
 Compound Info 
(S)-N-(5-(3-hydroxypicolinamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C28H26N6O3S
  1
1
IC50 = 31 nM
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CP0835239
 Compound Info 
(S)-N-(5-(2-(methylamino)benzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H30N6O2S
  1
1
IC50 = 41 nM
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CP0914610
 Compound Info 
(S)-N-(5-(2-hydroxy-5-methoxybenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H29N5O4S
  1
1
IC50 = 43 nM
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CP0960351
 Compound Info 
2-(5-Hydroxy-2-methyl-1H-indol-3-yl)-N-((S)-1-(4-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)pentyl)propanamide
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C30H33N5O3
  1
1
IC50 = 55.2 nM
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CP0552593
 Compound Info 
US10301323, Compound D1
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C21H20N4O
  1
1
IC50 = 80 nM
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CP0942943
 Compound Info 
(S)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)-5-(2-(methylthio)benzamido)pentyl)thiazole-5-carboxamide
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C30H30N6O3S2
  1
1
IC50 = 114 nM
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CP0961838
 Compound Info 
(S)-N-(5-(2-methoxybenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H29N5O3S
  1
1
IC50 = 150 nM
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CP0960834
 Compound Info 
(S)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)pentyl)-1-methylazetidine-3-carboxamide
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C23H29N5O2
  1
1
IC50 = 160 nM
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CP0955788
 Compound Info 
(S)-N-(5-(2-cyclopropylbenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C32H31N5O2S
  1
1
IC50 = 170 nM
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CP0951201
 Compound Info 
2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-((S)-1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)pentyl)propanamide
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C31H35N5O3
  1
1
IC50 = 210 nM
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CP0951203
 Compound Info 
(S)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)butyl)-1-methylazetidine-3-carboxamide
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C22H27N5O2
  1
1
IC50 = 300 nM
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CP0951199
 Compound Info 
(S)-2-(1H-indol-3-yl)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)pentyl)acetamide
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C28H29N5O2
  1
1
IC50 = 340 nM
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CP0914177
 Compound Info 
(S)-2-(5-methoxy-1H-indol-3-yl)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)pentyl)acetamide
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C29H31N5O3
  1
1
IC50 = 360 nM
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CP0914609
 Compound Info 
(S)-N-(5-(2-fluoro-6-methoxybenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H28FN5O3S
  1
1
IC50 = 420 nM
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CP0928238
 Compound Info 
(S)-N-(5-(2-(ethylthio)benzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C31H31N5O2S2
  1
1
IC50 = 670 nM
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CP0902997
 Compound Info 
(S)-N-(5-(2-chlorobenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C29H26ClN5O2S
  1
1
IC50 = 760 nM
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CP0898602
 Compound Info 
(S)-N-(5-(2-hydroxy-6-methoxybenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H29N5O4S
  1
1
IC50 = 810 nM
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CP0350774
 Compound Info 
N-[(1S)-1-[5-(2-methoxyquinolin-3-yl)-1,3,4-oxadiazol-2-yl]-5-[(2-methylsulfanylbenzoyl)amino]pentyl]-1,3-thiazole-5-carboxamide
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C29H28N6O4S2
  1
1
IC50 = 857 nM
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CP0749709
 Compound Info 
(S)-N-(5-(2-hydroxy-4-methoxybenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H29N5O4S
  1
1
IC50 = 1000 nM
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CP0840085
 Compound Info 
(S)-N-(5-(3-aminopicolinamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C28H27N7O2S
  1
1
IC50 = 1100 nM
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CP0902876
 Compound Info 
(S)-N-(5-(2-mercaptobenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C29H27N5O2S2
  1
1
IC50 = 1200 nM
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CP0958717
 Compound Info 
(S)-N-(5-(2-ethylbenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C31H31N5O2S
  1
1
IC50 = 1200 nM
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CP0928234
 Compound Info 
(S)-N-(5-(2,3-dihydro-1H-indene-4-carboxamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C32H31N5O2S
  1
1
IC50 = 1800 nM
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CP0946826
 Compound Info 
(S)-N-(5-(2-(1H-pyrrol-1-yl)benzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C33H30N6O2S
  1
1
IC50 = 1900 nM
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CP0951202
 Compound Info 
(S)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)hexyl)-1-methylazetidine-3-carboxamide
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C24H31N5O2
  1
1
IC50 = 3500 nM
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CP0882461
 Compound Info 
(S)-N-(1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)-5-(2-(trifluoromethoxy)benzamido)pentyl)thiazole-5-carboxamide
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C30H26F3N5O3S
  1
1
IC50 = 3900 nM
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CP0902996
 Compound Info 
(S)-N-(5-(2-(dimethylamino)benzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C31H32N6O2S
  1
1
IC50 = 5000 nM
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CP0906814
 Compound Info 
(S)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)nonyl)-1-methylazetidine-3-carboxamide
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C27H37N5O2
  1
1
IC50 = 5200 nM
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CP0208472
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-(2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
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C23H23N5O3S
  2
1
IC50 = 6700 nM
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2
IC50 = 7000 nM
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CP0882463
 Compound Info 
(S)-N-(5-(2-cyanobenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H26N6O2S
  1
1
IC50 = 7300 nM
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CP0902998
 Compound Info 
N-((1S)-5-(2-(methylsulfinyl)benzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H29N5O3S2
  1
1
IC50 = 7300 nM
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CP0882462
 Compound Info 
(S)-N-(1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)-5-(2-(2,2,2-trifluoroethoxy)benzamido)pentyl)thiazole-5-carboxamide
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C31H28F3N5O3S
  1
1
IC50 = 12000 nM
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CP0565121
 Compound Info 
N-[[5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl]methyl]-1-methylazetidine-3-carboxamide
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C19H21N5O2
  1
1
IC50 = 15000 nM
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CP0767213
 Compound Info 
(S)-N-(5-(2-hydroxy-3-methoxybenzamido)-1-(5-(naphthalen-2-yl)-1H-imidazol-2-yl)pentyl)thiazole-5-carboxamide
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C30H29N5O4S
  1
1
IC50 = 24000 nM
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CP0965923
 Compound Info 
(S)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)propyl)-1-methylazetidine-3-carboxamide
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C21H25N5O2
  1
1
IC50 = 28000 nM
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CP0962479
 Compound Info 
(S)-N-(1-(5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl)ethyl)-1-methylazetidine-3-carboxamide
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C20H23N5O2
  1
1
IC50 > 50000 nM
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