4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide

4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1S,5S)-3-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-phenyl-propyl}-amide

N-[(1S)-1-(4-aminophenyl)-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-4,4-difluorocyclohexane-1-carboxamide

US9107954, 1

N-[(1S)-1-[4-[[2-[2-[7-[[2-[2-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]heptylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-4,4-difluorocyclohexane-1-carboxamide

4,4-difluoro-N-[(1S)-1-[3-[[2-[2-[7-[[2-[2-(methylamino)-2-oxoethoxy]acetyl]amino]heptylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]cyclohexane-1-carboxamide

4,4-difluoro-N-[(1S)-1-[4-[[2-[2-[9-[[2-[2-(methylamino)-2-oxoethoxy]acetyl]amino]nonylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]cyclohexane-1-carboxamide

N-[(1S)-1-[4-[[2-[2-[9-[[2-[2-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]nonylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-4,4-difluorocyclohexane-1-carboxamide

4,4-difluoro-N-[(1S)-1-[4-[[2-[2-[7-[[2-[2-(methylamino)-2-oxoethoxy]acetyl]amino]heptylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]cyclohexane-1-carboxamide

4,4-difluoro-N-[(1S)-1-[4-[[2-[2-[7-[[2-[2-(methylamino)-2-oxoethoxy]acetyl]amino]heptylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]cyclohexane-1-carboxamide

4,4-difluoro-N-[(1S)-1-[4-[[2-[2-[5-[[2-[2-(methylamino)-2-oxoethoxy]acetyl]amino]pentylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]cyclohexane-1-carboxamide

N-[(1S)-1-[3-[[2-[2-[7-[[2-[2-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]heptylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-4,4-difluorocyclohexane-1-carboxamide

6,8-bis(benzamidomethyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

tert-butyl N-[4-[(1S)-1-[(4,4-difluorocyclohexanecarbonyl)amino]-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]phenyl]carbamate

N-[(1S)-1-[4-[[2-[2-[5-[[2-[2-[[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]amino]-2-oxoethoxy]acetyl]amino]pentylamino]-2-oxoethoxy]acetyl]amino]phenyl]-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]-4,4-difluorocyclohexane-1-carboxamide

7,9-di((E)-dec-1-enyl)-6,8-dimethyl-1,2,3,4-tetrahydroquinolizinium chloride

N-[5-[4-[(4-methylsulfanylphenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

Aanibamine

Anibamine

N-[5-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[5-[4-[(4-nitrophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

6,8-di((E)-dec-1-enyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

6,8-Didecyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

4,4-difluoro-N-[(1S)-1-[4-[[2-[2-(methylamino)-2-oxoethoxy]acetyl]amino]phenyl]-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]propyl]cyclohexane-1-carboxamide

1,3-di((Z)-dec-1-enyl)-2,4-dimethyl-7,8,9,10-tetrahydro-6H-pyrido[1,2-a]azepinium chloride

8-Dec-1-(Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

6-((E)-dec-1-enyl)-8-((Z)-dec-1-enyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

8-Dec-1-(E)-enyl-5,7-dimethyl-2,3-dihydro-1Hindolizinium chloride

methyl 4-[[4-[4-propan-2-yloxy-3-(pyrazine-2-carbonylamino)phenyl]piperazin-1-yl]methyl]benzoate

7,9-di((Z)-dec-1-enyl)-6,8-dimethyl-1,2,3,4-tetrahydroquinolizinium chloride

8-((E)-dec-1-enyl)-6-((Z)-dec-1-enyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

N-[5-(4-benzylpiperazin-1-yl)-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

8-Decyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

6,8-bis((2-naphthamido)methyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

4-cyclohexyl-N-[[8-[[(4-cyclohexylbenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride

6-Dec-1-(E)-enyl-5,7-dimethyl-2,3-dihydro-1Hindolizinium chloride

7,9-didecyl-6,8-dimethyl-1,2,3,4-tetrahydroquinolizinium chloride

6-Dec-1-(Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

6-Decyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

N-[5-[4-[(2-nitrophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[[5,7-dimethyl-8-[[(4-phenylbenzoyl)amino]methyl]-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]-4-phenylbenzamide;chloride

5,7-dimethyl-6,8-bis((4-methylbenzamido)methyl)-2,3-dihydro-1H-indolizinium chloride

N-[[5,7-dimethyl-8-[[(4-methylsulfanylbenzoyl)amino]methyl]-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]-4-methylsulfanylbenzamide;chloride

N-[5-[4-[(4-methoxyphenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[5-[4-[(4-bromophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

6,8-bis((4-ethylbenzamido)methyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

N-[5-[4-[(4-acetamidophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[[5,7-dimethyl-8-[[(4-propan-2-ylbenzoyl)amino]methyl]-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]-4-propan-2-ylbenzamide;chloride

N-[5-[4-[(4-aminophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[2-ethoxy-5-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]phenyl]benzamide

N-[5-[4-[[4-(dimethylamino)phenyl]methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[2-methoxy-5-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]phenyl]benzamide

3-[(Z)-dec-1-enyl]-2,4,6-trimethylpyridine

3-[(Z)-dec-1-enyl]-6-(3-methoxypropyl)-2,4-dimethylpyridine

3,5-bis[(Z)-dec-1-enyl]-2-(3-methoxypropyl)-4,6-dimethylpyridine

3-[(Z)-dec-1-enyl]-2-(3-methoxypropyl)-4,6-dimethylpyridine

4-tert-butyl-N-[[8-[[(4-tert-butylbenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride

1,3-didecyl-2,4-dimethyl-7,8,9,10-tetrahydro-6H-pyrido[1,2-a]azepinium chloride

4-bromo-N-[[8-[[(4-bromobenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride

N-[5-[1-[(4-aminophenyl)methyl]piperidin-4-yl]-2-methoxyphenyl]pyrazine-2-carboxamide

4-[[4-[4-propan-2-yloxy-3-(pyrazine-2-carbonylamino)phenyl]piperazin-1-yl]methyl]benzoic acid

N-[5-[1-[(4-aminophenyl)methyl]piperidin-4-yl]-2-ethoxyphenyl]pyrazine-2-carboxamide

N-[5-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]benzamide

N-[5-[4-[(4-methylsulfonylphenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[5-[4-[(4-methylphenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

4-chloro-N-[[8-[[(4-chlorobenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride

N-[5-[1-[(4-acetamidophenyl)methyl]piperidin-4-yl]-2-ethoxyphenyl]pyrazine-2-carboxamide

N-[5-[4-[[4-(diethylamino)phenyl]methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

1,3-di((E)-dec-1-enyl)-2,4-dimethyl-7,8,9,10-tetrahydro-6H-pyrido[1,2-a]azepinium chloride

N-[5-[4-[(3,5-dinitrophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

methyl 4-[[4-[4-propan-2-yloxy-3-(pyrazine-2-carbonylamino)phenyl]piperazin-1-yl]methyl]benzenesulfonate

N-[5-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[5-[4-[(3-nitrophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[5-[4-[(4-cyanophenyl)methyl]piperazin-1-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[5-[1-[[4-(diethylamino)phenyl]methyl]piperidin-4-yl]-2-ethoxyphenyl]pyrazine-2-carboxamide

N-[5-[1-[[4-(diethylamino)phenyl]methyl]piperidin-4-yl]-2-methoxyphenyl]pyrazine-2-carboxamide

N-[5-[1-[(4-acetamidophenyl)methyl]piperidin-4-yl]-2-methoxyphenyl]pyrazine-2-carboxamide

N-[5-[1-[[4-(diethylamino)phenyl]methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[2-ethoxy-5-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]phenyl]pyrazine-2-carboxamide

N-[5-[1-[(4-aminophenyl)methyl]piperidin-4-yl]-2-ethoxyphenyl]benzamide

N-[5-[1-[[4-(diethylamino)phenyl]methyl]piperidin-4-yl]-2-ethoxyphenyl]benzamide

N-[5-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[5-[1-[(4-aminophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]benzamide

N-[[5,7-dimethyl-8-[[(4-nitrobenzoyl)amino]methyl]-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]-4-nitrobenzamide;chloride

6,8-bis((4-methoxybenzamido)methyl)-5,7-dimethyl-2,3-dihydro-1H-indolizinium chloride

N-[5-[1-[(4-acetamidophenyl)methyl]piperidin-4-yl]-2-methoxyphenyl]benzamide

N-[2-methoxy-5-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]phenyl]pyrazine-2-carboxamide

N-[5-[1-[(4-aminophenyl)methyl]piperidin-4-yl]-2-methoxyphenyl]benzamide

N-[5-[1-[(4-aminophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

4-fluoro-N-[[8-[[(4-fluorobenzoyl)amino]methyl]-5,7-dimethyl-2,3-dihydro-1H-indolizin-4-ium-6-yl]methyl]benzamide;chloride

N-[5-[1-[(4-acetamidophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]pyrazine-2-carboxamide

N-[5-[1-[[4-(diethylamino)phenyl]methyl]piperidin-4-yl]-2-methoxyphenyl]benzamide

N-[5-[1-[(4-acetamidophenyl)methyl]piperidin-4-yl]-2-propan-2-yloxyphenyl]benzamide

3,5-bis[(Z)-dec-1-enyl]-2,4,6-trimethylpyridine