Brief Information of the Cell Line and Protein
Cell Line ID: CL000111 , MDA-MB-231
 Cell Line Info 
Synonyms
MDA_MB_231
MDA-MB 231
MDA.MB.231
MDA MB 231
MDA MB231
MDA Mb231
MDA-MB231
MDAMB-231
MDAMB231
MDA-231
MDA-231P
MDA231
MDA231-BRE
MB231
MD Anderson-Metastatic Breast-231
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0062
Protein ID: PT01771 , E3 ubiquitin-protein ligase Mdm2
 Protein Info 
Gene Name MDM2
Organism Homo sapiens, Human
Protein Classification Other nuclear protein
Uniprot ID Q00987
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000111
 Cell Line Info 
 Protein ID: PT01771
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0208613
 Compound Info 
1,4-benzodiazepine-2,5-dione, 12k
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C31H34Cl2IN5O2
  1
1
IC50 = 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0156321
 Compound Info 
1,4-benzodiazepine-2,5-dione scaffold, 22
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C29H29Cl2IN4O3
  1
1
IC50 = 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0341991
 Compound Info 
1,4-benzodiazepine-2,5-dione, 12j
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C32H32Cl2N4O3
  1
1
IC50 = 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0276930
 Compound Info 
1,4-benzodiazepine-2,5-dione antagonist, 24
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C31H28Cl2N2O4
  1
1
IC50 = 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0344398
 Compound Info 
1,4-benzodiazepine-2,5-dione antagonist, 21
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C29H25ClF3IN2O4
  1
1
IC50 = 30000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0824303
 Compound Info 
5-((S)-3-(4-chlorophenyl)-4-(1-(4-chlorophenyl)-2-(diethylamino)-2-oxoethyl)-7-iodo-2,5-dioxo-2,3,4,5-tetrahydrobenzo[e][1,4]diazepin-1-yl)pentanoic acid
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C32H32Cl2IN3O5
  1
1
IC50 = 37000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0285207
 Compound Info 
1,4-benzodiazepine-2,5-dione scaffold, 21
   Show/Hide
C28H28Cl2IN3O4
  1
1
IC50 = 57000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0441433
 Compound Info 
1,4-benzodiazepine-2,5-dione antagonist, 17
   Show/Hide
C27H23Cl2IN2O4
  1
1
IC50 = 60000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0051519
 Compound Info 
1,4-benzodiazepine-2,5-dione, 12b
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C28H25Cl2IN2O4
  1
1
IC50 = 67000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0170480
 Compound Info 
1,4-benzodiazepine-2,5-dione antagonist, 22
   Show/Hide
C29H25ClF3IN2O5
  1
1
IC50 = 67000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0938798
 Compound Info 
5-((S)-3-(4-chlorophenyl)-4-(1-(4-chlorophenyl)-2-methoxy-2-oxoethyl)-7-iodo-2,5-dioxo-2,3,4,5-tetrahydrobenzo[e][1,4]diazepin-1-yl)pentanoic acid
   Show/Hide
C29H25Cl2IN2O6
  1
1
IC50 = 67000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0276931
 Compound Info 
1,4-benzodiazepine-2,5-dione antagonist, 23
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C30H26Cl2N2O4
  1
1
IC50 = 69000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0340172
 Compound Info 
1,4-benzodiazepine-2,5-dione antagonist, 2
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C24H17Cl2IN2O4
  1
1
IC50 = 70000 nM
 Bioactivity Info 
   TI
   LI
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CP0340169
 Compound Info 
1,4-benzodiazepine-2,5-dione scaffold, 2
   Show/Hide
C28H26Cl2IN3O4
  1
1
IC50 = 80000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0370425
 Compound Info 
1,4-benzodiazepine-2,5-dione antagonist, 5
   Show/Hide
C28H24Cl2IN3O5
  1
1
IC50 = 90000 nM
 Bioactivity Info 
   TI
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   TS