Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-((S)-3-(4-chlorophenyl)-4-(1-(4-chlorophenyl)-2-methoxy-2-oxoethyl)-7-iodo-2,5-dioxo-2,3,4,5-tetrahydrobenzo[e][1,4]diazepin-1-yl)pentanoic acid
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 PubChem ID
CID: 44412055
Canonical SMILES
COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
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Compound Formula C29H25Cl2IN2O6
Compound Structure
Protein Name
 Protein Info 
E3 ubiquitin-protein ligase Mdm2
Protein Classification
Other nuclear protein
Uniprot ID
Q00987
Gene Name
MDM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 25000 nM
   TI
   LI
   LO
   TS
CL000111 MDA-MB-231
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 67000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2820 nM