| Compound ID |
Compound Name |
Compound Formula |
|
CP0341308
|
N-[1-(cyclohexylmethyl)piperidin-4-yl]-6-methoxy-7-(3-piperidin-1-ylpropoxy)-2-(4-propan-2-yl-1,4-diazepan-1-yl)quinazolin-4-amine
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|
C37H61N7O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0042224
|
N-(1-cyclohexylpiperidin-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)-2-(4-propan-2-yl-1,4-diazepan-1-yl)quinazolin-4-amine
Show/Hide
|
C36H59N7O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0281327
|
6-methoxy-7-(3-piperidin-1-ylpropoxy)-2-(4-propan-2-yl-1,4-diazepan-1-yl)-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C33H55N7O2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0241960
|
N-(1-cyclohexylpiperidin-4-yl)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C34H55N7O2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0350264
|
2-(4-benzyl-1,4-diazepan-1-yl)-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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|
C36H53N7O2
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0046275
|
2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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|
C30H47N5O2
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0350263
|
2-[4-(cyclohexylmethyl)-1,4-diazepan-1-yl]-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C36H59N7O2
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0158696
|
2-(azepan-1-yl)-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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|
C30H48N6O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0241952
|
2-(4-cyclohexyl-1,4-diazepan-1-yl)-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C35H57N7O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0154811
|
2-(4,4-difluoropiperidin-1-yl)-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
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|
C29H44F2N6O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0203470
|
6-methoxy-2-piperidin-1-yl-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C29H46N6O2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0345772
|
2-cyclohexyl-7-[2-[2-(dimethylamino)ethoxy]ethoxy]-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
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|
C29H47N5O3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0338455
|
6-methoxy-2-morpholin-4-yl-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C28H44N6O3
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0281325
|
6-methoxy-2-(4-phenyl-1,4-diazepan-1-yl)-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C35H51N7O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0344006
|
2-(azepan-1-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C31H50N6O2
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0043967
|
2-cyclohexyl-6-methoxy-7-(3-piperidin-1-ylpropoxy)-N-(1-propan-2-ylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C31H49N5O2
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0209417
|
N-(1-cyclopropylpiperidin-4-yl)-2-(4,4-difluoropiperidin-1-yl)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C29H42F2N6O2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0224989
|
6-methoxy-2-(oxan-4-yl)-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C29H45N5O3
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0291908
|
6-methoxy-2-(4-propan-2-yl-1,4-diazepan-1-yl)-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C32H53N7O2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0281324
|
2-(4-ethyl-1,4-diazepan-1-yl)-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C31H51N7O2
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0290010
|
6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C30H49N7O2
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0242458
|
N-(1-cyclopropylpiperidin-4-yl)-2-(1,1-dioxo-1,4-thiazinan-4-yl)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C28H42N6O4S
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0040710
|
6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine
Show/Hide
|
C29H47N7O2
|
1
|
| 1 |
IC50 = 910 nM
|
|
|
|
CP0222876
|
6-Methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
Show/Hide
|
C28H45N7O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0040703
|
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Show/Hide
|
C28H38N6O2
|
1
|
| 1 |
IC50 = 4563 nM
|
|
|
|
CP0455405
|
N-[2-[[4-[(1-benzylpiperidin-4-yl)amino]-7-methoxyquinazolin-2-yl]amino]ethyl]-N'-hydroxyheptanediamide
Show/Hide
|
C30H41N7O4
|
1
|
| 1 |
IC50 = 7136 nM
|
|
|
|
CP0231500
|
7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C27H45N7O3
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0392350
|
N-hydroxy-7-[6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-4-[(1-propan-2-ylpiperidin-4-yl)amino]quinazolin-7-yl]oxyheptanamide
Show/Hide
|
C30H49N7O4
|
1
|
| 1 |
IC50 = 27370 nM
|
|
|
|
CP0538077
|
N-[2-[[4-[(1-benzylpiperidin-4-yl)amino]-7-methoxyquinazolin-2-yl]amino]ethyl]-N'-hydroxyoctanediamide
Show/Hide
|
C31H43N7O4
|
1
|
| 1 |
IC50 = 37790 nM
|
|
|
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CP0566620
|
N'-hydroxy-N-[2-[[7-methoxy-4-[(1-methylpiperidin-4-yl)amino]quinazolin-2-yl]amino]ethyl]heptanediamide
Show/Hide
|
C24H37N7O4
|
1
|
| 1 |
IC50 = 46830 nM
|
|
|
|
CP0482390
|
N'-[2-[[7-methoxy-4-[(1-methylpiperidin-4-yl)amino]quinazolin-2-yl]amino]ethyl]-N-methylhexanediamide
Show/Hide
|
C24H37N7O3
|
1
|
| 1 |
IC50 = 46970 nM
|
|
|
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CP0039320
|
7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Show/Hide
|
C26H43N7O2
|
1
|
| 1 |
IC50 > 5000 nM
|
|
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