Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
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 PubChem ID
CID: 25150857
SID: 163596611
Canonical SMILES
COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N1CCCN(C)CC1
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Compound Formula C28H38N6O2
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EHMT2
Protein Classification
Epigenetic regulator
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Protein methyltransferase
Uniprot ID
Q96KQ7
Gene Name
EHMT2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000111 MDA-MB-231
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4563 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 67 nM
2 IC50 = 110 nM
3 IC50 = 180 nM
4 IC50 = 290 nM
5 IC50 = 1200 nM
6 IC50 = 1700 nM
7 IC50 = 1900 nM
8 IC50 = 2000 nM
9 IC50 = 2700 nM
10 Kd = 130 nM