| Compound ID |
Compound Name |
Compound Formula |
|
CP0029048
|
8-bromo-2-[(2S)-pyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C14H12BrN3O2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0028591
|
8-bromo-2-[(2S,4R)-4-fluoropyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C14H11BrFN3O2
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0029051
|
8-chloro-2-[(2S)-pyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C14H12ClN3O2
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0029052
|
8-chloro-2-[(2S,4R)-4-fluoropyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C14H11ClFN3O2
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0017521
|
2-[(2S,4R)-4-fluoropyrrolidin-2-yl]-8-methoxy-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C15H14FN3O3
|
1
|
| 1 |
IC50 = 292 nM
|
|
|
|
CP0015976
|
8-bromo-2-(pyrrolidin-1-ylmethyl)-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C15H14BrN3O2
|
1
|
| 1 |
IC50 = 353 nM
|
|
|
|
CP0019368
|
8-bromo-2-[[(3S)-3-methoxypyrrolidin-1-yl]methyl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C16H16BrN3O3
|
1
|
| 1 |
IC50 = 362 nM
|
|
|
|
CP0017519
|
8-bromo-2-[(2S,4R)-4-hydroxypyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C14H12BrN3O3
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0029050
|
8-bromo-2-[(2S,4S)-4-fluoropyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
Show/Hide
|
C14H11BrFN3O2
|
1
|
| 1 |
IC50 = 566 nM
|
|
|
|
CP0028730
|
2-[[(3S)-3-aminopyrrolidin-1-yl]methyl]-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C15H15BrN4O2
|
1
|
| 1 |
IC50 = 625 nM
|
|
|
|
CP0029049
|
8-bromo-2-[(2S)-1-methylpyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
Show/Hide
|
C15H14BrN3O2
|
1
|
| 1 |
IC50 = 802 nM
|
|
|
|
CP0028590
|
2-(1-aminoethyl)-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C12H10BrN3O2
|
1
|
| 1 |
IC50 = 874 nM
|
|
|
|
CP0017520
|
8-methoxy-2-[(2S)-pyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
Show/Hide
|
C15H15N3O3
|
1
|
| 1 |
IC50 = 1374 nM
|
|
|
|
CP0024314
|
8-bromo-2-piperidin-4-yl-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C15H14BrN3O2
|
1
|
| 1 |
IC50 = 1434 nM
|
|
|
|
CP0030751
|
8-bromo-2-[[(3S)-3-hydroxypyrrolidin-1-yl]methyl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
Show/Hide
|
C15H14BrN3O3
|
1
|
| 1 |
IC50 = 1471 nM
|
|
|
|
CP0025519
|
8-bromo-2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
Show/Hide
|
C15H14BrN3O3
|
1
|
| 1 |
IC50 = 1805 nM
|
|
|
|
CP0019369
|
8-bromo-2-piperidin-3-yl-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C15H14BrN3O2
|
1
|
| 1 |
IC50 = 2356 nM
|
|
|
|
CP0031225
|
2-(azetidin-3-yl)-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C13H10BrN3O2
|
1
|
| 1 |
IC50 = 2536 nM
|
|
|
|
CP0018916
|
8-bromo-2-[(2R)-pyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
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|
C14H12BrN3O2
|
1
|
| 1 |
IC50 = 4592 nM
|
|
|
|
CP0031224
|
1-[(8-bromo-4-oxo-3H-[1]benzofuro[3,2-d]pyrimidin-2-yl)methyl]pyrrolidine-3-carboxylic acid
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|
C16H14BrN3O4
|
1
|
| 1 |
IC50 > 40000 nM
|
|
|
