| Compound ID |
Compound Name |
Compound Formula |
|
CP0169882
|
6-[6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
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|
C19H15ClN4O2S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0436386
|
3-[6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylbenzoic acid
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|
C20H16ClN3O2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0417002
|
(3,5-dichlorophenyl)methyl (3R)-3-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]pyrrolidine-1-carboxylate
Show/Hide
|
C36H52Cl2N2O5
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
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CP0160899
|
6-[(6-chloro-2-methyl-1H-indol-3-yl)sulfanyl]pyridine-2-carboxylic acid
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|
C15H11ClN2O2S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0196587
|
6-[2,6-dimethyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
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|
C20H18N4O2S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
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CP0160896
|
6-(6-chloro-1,2-dimethylindol-3-yl)sulfanylpyridine-2-carboxylic acid
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|
C16H13ClN2O2S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
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CP0160898
|
3-(6-chloro-2-methyl-1-phenylindol-3-yl)sulfanylbenzoic acid
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|
C22H16ClNO2S
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0497905
|
(3,5-dichlorophenyl)methyl N-[[1-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]-4-hydroxypiperidin-4-yl]methyl]carbamate
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|
C38H56Cl2N2O6
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0320335
|
6-[6-methoxy-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0454534
|
(3,5-dichlorophenyl)methyl 4-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]piperazine-1-carboxylate
Show/Hide
|
C36H52Cl2N2O5
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0454533
|
(3,5-dichlorophenyl)methyl N-[2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethyl]carbamate
Show/Hide
|
C34H50Cl2N2O5
|
1
|
| 1 |
IC50 = 202 nM
|
|
|
|
CP0566955
|
(3,5-dichlorophenyl)methyl N-[3-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]cyclobutyl]carbamate
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|
C36H52Cl2N2O5
|
1
|
| 1 |
IC50 = 208 nM
|
|
|
|
CP0190213
|
6-[5-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C19H15ClN4O2S
|
1
|
| 1 |
IC50 = 258 nM
|
|
|
|
CP0567182
|
(3,5-dichlorophenyl)methyl N-[(3R)-1-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]pyrrolidin-3-yl]carbamate
Show/Hide
|
C36H52Cl2N2O5
|
1
|
| 1 |
IC50 = 313 nM
|
|
|
|
CP0181435
|
6-[[6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]methyl]pyridine-2-carboxylic acid
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|
C20H17ClN4O2
|
1
|
| 1 |
IC50 = 339 nM
|
|
|
|
CP0169880
|
6-[6-fluoro-2-methyl-1-(1-methylpyrazol-3-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C19H15FN4O2S
|
1
|
| 1 |
IC50 = 349 nM
|
|
|
|
CP0564944
|
(3,5-dichlorophenyl)methyl N-[(3S)-1-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]pyrrolidin-3-yl]carbamate
Show/Hide
|
C36H52Cl2N2O5
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0558523
|
(3,5-dichlorophenyl)methyl N-[3-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]carbamate
Show/Hide
|
C35H52Cl2N2O5
|
1
|
| 1 |
IC50 = 563 nM
|
|
|
|
CP0516045
|
3-[[6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]methyl]benzoic acid
Show/Hide
|
C21H18ClN3O2
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0417003
|
(3,5-dichlorophenyl)methyl (3S)-3-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]pyrrolidine-1-carboxylate
Show/Hide
|
C36H52Cl2N2O5
|
1
|
| 1 |
IC50 = 717 nM
|
|
|
|
CP0160900
|
3-[6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]oxybenzoic acid
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|
C20H16ClN3O3
|
1
|
| 1 |
IC50 = 726 nM
|
|
|
|
CP0169877
|
3-[(6-chloro-2-methyl-1H-indol-3-yl)sulfanyl]benzoic acid
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|
C16H12ClNO2S
|
1
|
| 1 |
IC50 = 747 nM
|
|
|
|
CP0417004
|
(3,5-dichlorophenyl)methyl 4-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentyl]piperazine-1-carboxylate
Show/Hide
|
C36H54Cl2N2O4
|
1
|
| 1 |
IC50 = 814 nM
|
|
|
|
CP0567129
|
(3,5-dichlorophenyl)methyl 3-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]azetidine-1-carboxylate
Show/Hide
|
C35H50Cl2N2O5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0324028
|
3-(6-chloro-1,2-dimethylindol-3-yl)sulfanylbenzoic acid
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|
C17H14ClNO2S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0181433
|
6-[2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C19H16N4O2S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
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CP0432845
|
2-[(3,5-dichlorophenyl)methyl]-7-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]-5,6,8,8a-tetrahydro-1H-imidazo[1,5-a]pyrazin-3-one
Show/Hide
|
C37H53Cl2N3O4
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
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CP0497906
|
(3,5-dichlorophenyl)methyl 4-[[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]methyl]piperidine-1-carboxylate
Show/Hide
|
C38H56Cl2N2O5
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
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CP0169879
|
4-[2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylbutanoic acid
Show/Hide
|
C17H19N3O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0196588
|
6-[2,4-dimethyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
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|
C20H18N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0375715
|
2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonic acid
Show/Hide
|
C26H45NO6S
|
1
|
| 1 |
IC50 = 10300 nM
|
|
|
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CP0241337
|
6-[(6-fluoro-2-methyl-1H-indol-3-yl)sulfanyl]pyridine-2-carboxylic acid
Show/Hide
|
C15H11FN2O2S
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
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CP0324027
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3-(6-chloro-1-cyclopentyl-2-methylindol-3-yl)sulfanylbenzoic acid
Show/Hide
|
C21H20ClNO2S
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
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CP0436385
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6-[(2-methyl-1H-indol-3-yl)sulfanyl]pyridine-2-carboxylic acid
Show/Hide
|
C15H12N2O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0441120
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6-(1-cyclopentyl-2-methylindol-3-yl)sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0447493
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4-[6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylbutanoic acid
Show/Hide
|
C17H18ClN3O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0465145
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6-(2-methyl-1-phenylindol-3-yl)sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C21H16N2O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0516042
|
6-[4-methoxy-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0558338
|
3-[[2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]methyl]benzoic acid
Show/Hide
|
C21H19N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0558339
|
6-[[2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]methyl]pyridine-2-carboxylic acid
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0562735
|
6-(1,2-dimethylindol-3-yl)sulfanylpyridine-2-carboxylic acid
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|
C16H14N2O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0563528
|
6-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indole
Show/Hide
|
C13H12ClN3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0565466
|
6-[4-chloro-2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C19H15ClN4O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0570218
|
3-[(2-methyl-1H-indol-3-yl)sulfanyl]benzoic acid
Show/Hide
|
C16H13NO2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0574925
|
3-[2-methyl-1-(1-methylpyrazol-4-yl)indol-3-yl]oxybenzoic acid
Show/Hide
|
C20H17N3O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0432846
|
(4R)-N-(2-aminoethyl)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanamide
Show/Hide
|
C26H46N2O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0562716
|
benzyl 4-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]piperazine-1-carboxylate
Show/Hide
|
C36H54N2O5
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0564945
|
benzyl N-[2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethyl]carbamate
Show/Hide
|
C34H52N2O5
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0567130
|
(4R)-N-[(3,5-dichlorophenyl)methyl]-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanamide
Show/Hide
|
C31H45Cl2NO3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0181431
|
6-(6-chloro-1-cyclopentyl-2-methylindol-3-yl)sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C20H19ClN2O2S
|
1
|
| 1 |
IC50 > 2800 nM
|
|
|
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CP0575978
|
6-[4-fluoro-2-methyl-1-(1-methylpyrazol-3-yl)indol-3-yl]sulfanylpyridine-2-carboxylic acid
Show/Hide
|
C19H15FN4O2S
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
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CP0169883
|
3-(2-methyl-1-phenylindol-3-yl)sulfanylbenzoic acid
Show/Hide
|
C22H17NO2S
|
1
|
| 1 |
IC50 > 5000 nM
|
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|
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CP0558337
|
6-[(2,4-dimethyl-1H-indol-3-yl)sulfanyl]pyridine-2-carboxylic acid
Show/Hide
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C16H14N2O2S
|
1
|
| 1 |
IC50 > 8000 nM
|
|
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