General Information of the Compound
Compound ID
CP0497905
Compound Name
(3,5-dichlorophenyl)methyl N-[[1-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]-4-hydroxypiperidin-4-yl]methyl]carbamate
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Structure
Formula
C38H56Cl2N2O6
Molecular Weight
707.78
Canonical SMILES
C[C@H](CCC(=O)N1CCC(O)(CNC(=O)OCc2cc(Cl)cc(Cl)c2)CC1)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
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InChI
InChI=1S/C38H56Cl2N2O6/c1-23(29-5-6-30-34-31(9-11-37(29,30)3)36(2)10-8-28(43)18-25(36)19-32(34)44)4-7-33(45)42-14-12-38(47,13-15-42)22-41-35(46)48-21-24-16-26(39)20-27(40)17-24/h16-17,20,23,25,28-32,34,43-44,47H,4-15,18-19,21-22H2,1-3H3,(H,41,46)/t23-,25+,28-,29-,30+,31+,32+,34+,36+,37-/m1/s1
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InChIKey
GPGVJAHUXFWIPP-NLPMUVRGSA-N
Physicochemical Property
logP
6.98
Rotatable Bonds
8
Heavy Atom Count
48
Polar Areas
119.33
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
6
Complexity
48

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137654233
ChEMBL ID
CHEMBL4093316
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01786, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000088 Flp-In-293 Homo sapiens (Human)  1
1
IC50 = 100 nM
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